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How to Choose the Right Lab Freezer for Your Research Needs

large laboratory with a lab freezer

When it comes to scientific research, your results depend largely on the integrity of your samples. They need to be properly maintained to achieve accurate, reliable results. One of the best ways to do this is by using a thermo scientific freezer—also known as a lab freezer. It plays a crucial role in keeping pharmaceutical, chemical, and biological materials viable, so selecting the proper model plays a significant role in your success. With an understanding of the factors at play—storage needs, temperature range, energy requirements, and product features, you can make a sound decision. Here’s what you should take into consideration when shopping for laboratory freezers.

Understand Your Storage Requirements

Don’t even start browsing until you have a grasp on all the types of samples you’ll need to store. Let’s take a glance at the three primary types of samples you’ll probably be storing and what they’ll require.

  • Biological Samples: These encompass bacteria, plasma, DNA and RNA, and require ultra-low temperatures—equal to or lower than -80ºC (-112ºF).
  • Chemical Samples: Since many chemicals have combustible properties, they may require a thermo scientific freezer that offers protection against fires and explosions.
  • Pharmaceuticals: These require specific temperatures to maintain their efficacy, so look for a freezer that prioritizes temperature precision.

Speaking of temperatures, let’s discuss the different degree ranges offered by laboratory freezers:

  • Standard: These generally operate at around -20ºC (-4ºF) and are a good option for storing general samples.
  • Ultra-Low Temperature: Able to maintain temperatures ranging from -80ºC to -86ºC (or -112ºF to -122.8ºF), these freezers are important for storing sensitive biological samples for long periods of time.
  • Cryogenic: These are required for storing highly sensitive applications such as materials for stem cell research, as they operate at temperatures below -150ºC (-238ºF). 

Consider the Freezer Type

There are different benefits offered by different types of freezers, so it’s important to take this factor into consideration when trying to choose the right model. Let’s take a look:

  • Upright Freezers: These provide easy access to samples, as well as shelving options that help with organization. Be aware, however, that temperature fluctuations are common because of the frequency of door openings.
  • Chest Freezers: These provide more stable temperatures, good energy-efficiency ratings, and higher storage capacity, but have considerably more bulk; it can also be difficult to access samples that are near the bottom.
  • Ultra-Low Temperature Freezers: These laboratory freezers are ideal for storing biological specimens for long periods of time, but be prepared to perform relatively frequent maintenance to maintain optimal performance.
  • Explosion-Proof and Flammable Storage Freezers: This is necessary if your laboratory is handling volatile chemicals, as a lack of sufficient storage for such chemicals is a serious safety risk. 

Evaluate Capacity and Space Constraints

Realizing you don’t have anywhere to put all your samples can bring your research momentum to a screeching halt, so it’s in your best interest to find a lab freezer that has plenty of storage capacity. Take stock of your inventory levels and plan your purchase accordingly. You’ll likely need no more than 10 cubic feet of storage for limited samples, but high-volume research will necessitate storage of over 25 cubic feet.

There’s more to consider than capacity alone, however. A unit with adjustable compartments and shelves will provide versatility and organization options. And finally, make sure your chosen lab freezer will fit in the space you’ve designated for it.

Energy Efficiency and Operational Costs

Your laboratory uses a lot of power, so it’s important to do what you can to minimize that usage—especially if your laboratory is operating with multiple freezers. While shopping around, be on the lookout for freezers with good ENERGY STAR® ratings. These models offer energy-saving features that can reduce your long-term costs.

It’s important to note that a high energy rating doesn’t necessarily mean the unit will function properly. That’s why combining this rating with other research on performance is key to choosing a model that will truly serve your needs while keeping costs low.

Features and Technology to Look For

These days, almost every lab freezer has a combination of features that enhance usability and security. It’s up to you to choose one that offers the features important to your research.

  • Digital Temperature Controls: These controls give you the ability to ensure precise temperature settings and minimize fluctuations.
  • Alarm Systems: If something is malfunctioning, the issue needs to be resolved as quickly as possible. Alarm systems will alert you the moment an issue or anomaly is detected so you can respond accordingly.
  • Backup Power Options: Prolonged lack of power can ruin every sample within a freezer, so backup functionality is crucial for keeping these samples viable if there’s a power outage.
  • Smart Connectivity and Cloud-Based Monitoring: Reliability is increased thanks to remote access and real-time monitoring capabilities.

Maintenance and Longevity

If you want to maximize the lifespan of your thermo scientific freezer and enjoy ideal performance, maintenance is a necessity. Make sure you’re operating on a regular cleaning schedule to maximize airflow and prevent ice buildup. Additionally, keep an eye on your freezer’s temperature readings and make any necessary setting tweaks. For the more involved repairs that may become necessary, for a variety of reasons, it’s recommended that you invest in a professional maintenance agreement. This will save you money on repairs when they’re needed and reduce equipment downtime, so your research isn’t disrupted and your samples aren’t ruined. 

Choose the Lab Freezer That Fits Your Needs

There are several considerations to make when choosing a lab freezer—features, maintenance needs, temperature requirements, capacity, and more. When you evaluate all these factors, you’ll have a better understanding of what kind of unit is best suited for your lab and research. If you’re looking for a place that offers numerous options, you’re already there. Our offerings of laboratory equipment are unmatched. Get in touch and equip your lab with everything you need!

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A Complete Guide to Biosafety Cabinet Types, Uses, and Maintenance

lab worker using a biosafety cabinet

Biological Safety Cabinets—or BSCs—are unsung heroes of the laboratory. They’re not as exciting as microscopes or centrifuges, but they’re vital components of scientific safety, nonetheless. They play a role in protecting not only laboratory personnel, but also the samples within the lab and the environment overall. But as with any other equipment type, not every biosafety cabinet is created equal; there are types, applications, maintenance practices, and more to take into consideration. In this blog, we want to take a look at all the options so you might be better informed when it’s time to purchase one for your own lab.

Biosafety Cabinet Types

Class I Biological Safety Cabinet

These provide environmental and personnel protection, but be warned that they don’t safeguard their actual contents. The primary role of a Class 1 cabinet is to prevent exposure to hazardous aerosols.

Some common applications include handling of biological materials that post low or moderate risk, procedures that include aerosol-generating processes, and the protection of lab employees working with non-sterile substances.

Class II Biological Safety Cabinet

This is where you’ll find the most variety. A combination of HEPA filtrations and controlled airflow results in the protection of people, the environment, and the product.

  • Class II, Type A1: 70% of the air within these cabinets is recirculated, making it suitable for low-risk operations.
  • Class II, Type A2: This is similar to A1, the main difference being greater inward air velocity. As a result, it’s much more suitable for handling hazardous agents.
  • Class II, Type B1: Type B1 expels 60% of its air, making it a good choice for any work that involves biological hazards and other volatile chemicals.
  • Class II, Type B2: This is a fully exhausted system that doesn’t allow any recirculation. It’s highly recommended when dealing with high-risk pathogens and toxic chemicals.

Regardless of subtype, a class II biological safety cabinet is an essential part of microbiology and pharmaceutical labs. It allows for the safe manipulation of infectious agents, cell-culture research, viral studies, and the preparation of sterile products.

Class III Biological Safety Cabinet

If you’re looking for the highest possible level of containment, you should be prioritizing class III cabinets. They operate as fully enclosed units with glove ports, and are meant for handling the most hazardous biological materials—including Biosafety Level 4 (BSL-4) pathogens.

Typically, class III cabinets are found serving the following industries and areas of research:

  • High-containment labs and bioweapons research
  • Highly infectious virus studies, such as research into Ebola
  • The development of vaccines and biopharmaceutical manufacturing

Common Biological Safety Cabinet Uses

To say these cabinets are important to several fields of research may be an understatement. In many cases, proper research can’t be conducted without them. Their common applications are plenty, but here are the primary uses:

  • Infectious agent containment in microbiology and virology
  • Drug formulation within the biotechnology and pharmaceutical industries
  • Diagnostic procedures in clinical and hospital laboratories
  • COVID-19 testing and research

Maintenance and Best Practices

With so many substances being handled within these cabinets, a bit of maintenance is to be expected. Here’s a short rundown of the bases you should be covering.

Regular Cleaning and Decontamination

Make sure you’re cleaning every surface with the appropriate disinfectants, such as 70% ethanol and bleach solutions. Do this before and after use. When cleaning is complete, autoclave or safely dispose of any contaminated waste materials.

Importance of Annual Certification

To ensure that your biosafety cabinet meets all industry standards (and functions properly), an annual certification is necessary. The tests involved in this certification include airflow validations, containment efficiency, and HEPA filter integrity checks.

Proper Airflow Management

When choosing a spot for your cabinet, ensure you allow plenty of space near the airflow grills to maintain circulation. In addition, train all personnel to follow proper hand and arm movement techniques to prevent turbulence.

Common Troubleshooting Tips

If you’re experiencing issues with your biosafety cabinet, here are some troubleshooting tips we suggest:

  • Low Airflow Alarms: Ensure no filters are clogged and inspect the blower motor.
  • HEPA Filter Saturation: Stick to a timely schedule of filter replacements for optimal airflow. Manufacturer guidelines should detail how frequently filters need to be changed.
  • Inconsistent Air Velocity: Minimize external airflow disturbances (like HVAC changes).

Choosing the Right Biosafety Cabinet for Your Needs

Before you make a final decision on which cabinet to purchase, you should carefully consider your research needs.

  • Work Type: Do you require protection for your people, the environment, your product, or a combination of the three?
  • Containment Level: It’s vital to get a biological safety cabinet that can handle the biosafety level (BSL-1 to BSL-4) of the substances you’ll be working with.
  • Lab Space and Configuration: Make sure you have enough space in your laboratory for the cabinet to have a permanent placement.
  • Regulatory Compliance: Make sure you adhere to standards set by OSHA, CDC, and NSF.

A Laboratory Necessity

The biosafety cabinet is an essential tool for any laboratory researching hazardous biological agents. By familiarizing yourself with different cabinet types, biosafety levels, and maintenance requirements, you can make an informed purchase for your lab’s needs. Whether you’re in the market for biosafety cabinets or you have some you need to sell, get in touch with us at BaneBio—the Scientific Supermarket.