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How to Choose the Right Lab Freezer for Your Research Needs

large laboratory with a lab freezer

When it comes to scientific research, your results depend largely on the integrity of your samples. They need to be properly maintained to achieve accurate, reliable results. One of the best ways to do this is by using a thermo scientific freezer—also known as a lab freezer. It plays a crucial role in keeping pharmaceutical, chemical, and biological materials viable, so selecting the proper model plays a significant role in your success. With an understanding of the factors at play—storage needs, temperature range, energy requirements, and product features, you can make a sound decision. Here’s what you should take into consideration when shopping for laboratory freezers.

Understand Your Storage Requirements

Don’t even start browsing until you have a grasp on all the types of samples you’ll need to store. Let’s take a glance at the three primary types of samples you’ll probably be storing and what they’ll require.

  • Biological Samples: These encompass bacteria, plasma, DNA and RNA, and require ultra-low temperatures—equal to or lower than -80ºC (-112ºF).
  • Chemical Samples: Since many chemicals have combustible properties, they may require a thermo scientific freezer that offers protection against fires and explosions.
  • Pharmaceuticals: These require specific temperatures to maintain their efficacy, so look for a freezer that prioritizes temperature precision.

Speaking of temperatures, let’s discuss the different degree ranges offered by laboratory freezers:

  • Standard: These generally operate at around -20ºC (-4ºF) and are a good option for storing general samples.
  • Ultra-Low Temperature: Able to maintain temperatures ranging from -80ºC to -86ºC (or -112ºF to -122.8ºF), these freezers are important for storing sensitive biological samples for long periods of time.
  • Cryogenic: These are required for storing highly sensitive applications such as materials for stem cell research, as they operate at temperatures below -150ºC (-238ºF). 

Consider the Freezer Type

There are different benefits offered by different types of freezers, so it’s important to take this factor into consideration when trying to choose the right model. Let’s take a look:

  • Upright Freezers: These provide easy access to samples, as well as shelving options that help with organization. Be aware, however, that temperature fluctuations are common because of the frequency of door openings.
  • Chest Freezers: These provide more stable temperatures, good energy-efficiency ratings, and higher storage capacity, but have considerably more bulk; it can also be difficult to access samples that are near the bottom.
  • Ultra-Low Temperature Freezers: These laboratory freezers are ideal for storing biological specimens for long periods of time, but be prepared to perform relatively frequent maintenance to maintain optimal performance.
  • Explosion-Proof and Flammable Storage Freezers: This is necessary if your laboratory is handling volatile chemicals, as a lack of sufficient storage for such chemicals is a serious safety risk. 

Evaluate Capacity and Space Constraints

Realizing you don’t have anywhere to put all your samples can bring your research momentum to a screeching halt, so it’s in your best interest to find a lab freezer that has plenty of storage capacity. Take stock of your inventory levels and plan your purchase accordingly. You’ll likely need no more than 10 cubic feet of storage for limited samples, but high-volume research will necessitate storage of over 25 cubic feet.

There’s more to consider than capacity alone, however. A unit with adjustable compartments and shelves will provide versatility and organization options. And finally, make sure your chosen lab freezer will fit in the space you’ve designated for it.

Energy Efficiency and Operational Costs

Your laboratory uses a lot of power, so it’s important to do what you can to minimize that usage—especially if your laboratory is operating with multiple freezers. While shopping around, be on the lookout for freezers with good ENERGY STAR® ratings. These models offer energy-saving features that can reduce your long-term costs.

It’s important to note that a high energy rating doesn’t necessarily mean the unit will function properly. That’s why combining this rating with other research on performance is key to choosing a model that will truly serve your needs while keeping costs low.

Features and Technology to Look For

These days, almost every lab freezer has a combination of features that enhance usability and security. It’s up to you to choose one that offers the features important to your research.

  • Digital Temperature Controls: These controls give you the ability to ensure precise temperature settings and minimize fluctuations.
  • Alarm Systems: If something is malfunctioning, the issue needs to be resolved as quickly as possible. Alarm systems will alert you the moment an issue or anomaly is detected so you can respond accordingly.
  • Backup Power Options: Prolonged lack of power can ruin every sample within a freezer, so backup functionality is crucial for keeping these samples viable if there’s a power outage.
  • Smart Connectivity and Cloud-Based Monitoring: Reliability is increased thanks to remote access and real-time monitoring capabilities.

Maintenance and Longevity

If you want to maximize the lifespan of your thermo scientific freezer and enjoy ideal performance, maintenance is a necessity. Make sure you’re operating on a regular cleaning schedule to maximize airflow and prevent ice buildup. Additionally, keep an eye on your freezer’s temperature readings and make any necessary setting tweaks. For the more involved repairs that may become necessary, for a variety of reasons, it’s recommended that you invest in a professional maintenance agreement. This will save you money on repairs when they’re needed and reduce equipment downtime, so your research isn’t disrupted and your samples aren’t ruined. 

Choose the Lab Freezer That Fits Your Needs

There are several considerations to make when choosing a lab freezer—features, maintenance needs, temperature requirements, capacity, and more. When you evaluate all these factors, you’ll have a better understanding of what kind of unit is best suited for your lab and research. If you’re looking for a place that offers numerous options, you’re already there. Our offerings of laboratory equipment are unmatched. Get in touch and equip your lab with everything you need!

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A Complete Guide to Biosafety Cabinet Types, Uses, and Maintenance

lab worker using a biosafety cabinet

Biological Safety Cabinets—or BSCs—are unsung heroes of the laboratory. They’re not as exciting as microscopes or centrifuges, but they’re vital components of scientific safety, nonetheless. They play a role in protecting not only laboratory personnel, but also the samples within the lab and the environment overall. But as with any other equipment type, not every biosafety cabinet is created equal; there are types, applications, maintenance practices, and more to take into consideration. In this blog, we want to take a look at all the options so you might be better informed when it’s time to purchase one for your own lab.

Biosafety Cabinet Types

Class I Biological Safety Cabinet

These provide environmental and personnel protection, but be warned that they don’t safeguard their actual contents. The primary role of a Class 1 cabinet is to prevent exposure to hazardous aerosols.

Some common applications include handling of biological materials that post low or moderate risk, procedures that include aerosol-generating processes, and the protection of lab employees working with non-sterile substances.

Class II Biological Safety Cabinet

This is where you’ll find the most variety. A combination of HEPA filtrations and controlled airflow results in the protection of people, the environment, and the product.

  • Class II, Type A1: 70% of the air within these cabinets is recirculated, making it suitable for low-risk operations.
  • Class II, Type A2: This is similar to A1, the main difference being greater inward air velocity. As a result, it’s much more suitable for handling hazardous agents.
  • Class II, Type B1: Type B1 expels 60% of its air, making it a good choice for any work that involves biological hazards and other volatile chemicals.
  • Class II, Type B2: This is a fully exhausted system that doesn’t allow any recirculation. It’s highly recommended when dealing with high-risk pathogens and toxic chemicals.

Regardless of subtype, a class II biological safety cabinet is an essential part of microbiology and pharmaceutical labs. It allows for the safe manipulation of infectious agents, cell-culture research, viral studies, and the preparation of sterile products.

Class III Biological Safety Cabinet

If you’re looking for the highest possible level of containment, you should be prioritizing class III cabinets. They operate as fully enclosed units with glove ports, and are meant for handling the most hazardous biological materials—including Biosafety Level 4 (BSL-4) pathogens.

Typically, class III cabinets are found serving the following industries and areas of research:

  • High-containment labs and bioweapons research
  • Highly infectious virus studies, such as research into Ebola
  • The development of vaccines and biopharmaceutical manufacturing

Common Biological Safety Cabinet Uses

To say these cabinets are important to several fields of research may be an understatement. In many cases, proper research can’t be conducted without them. Their common applications are plenty, but here are the primary uses:

  • Infectious agent containment in microbiology and virology
  • Drug formulation within the biotechnology and pharmaceutical industries
  • Diagnostic procedures in clinical and hospital laboratories
  • COVID-19 testing and research

Maintenance and Best Practices

With so many substances being handled within these cabinets, a bit of maintenance is to be expected. Here’s a short rundown of the bases you should be covering.

Regular Cleaning and Decontamination

Make sure you’re cleaning every surface with the appropriate disinfectants, such as 70% ethanol and bleach solutions. Do this before and after use. When cleaning is complete, autoclave or safely dispose of any contaminated waste materials.

Importance of Annual Certification

To ensure that your biosafety cabinet meets all industry standards (and functions properly), an annual certification is necessary. The tests involved in this certification include airflow validations, containment efficiency, and HEPA filter integrity checks.

Proper Airflow Management

When choosing a spot for your cabinet, ensure you allow plenty of space near the airflow grills to maintain circulation. In addition, train all personnel to follow proper hand and arm movement techniques to prevent turbulence.

Common Troubleshooting Tips

If you’re experiencing issues with your biosafety cabinet, here are some troubleshooting tips we suggest:

  • Low Airflow Alarms: Ensure no filters are clogged and inspect the blower motor.
  • HEPA Filter Saturation: Stick to a timely schedule of filter replacements for optimal airflow. Manufacturer guidelines should detail how frequently filters need to be changed.
  • Inconsistent Air Velocity: Minimize external airflow disturbances (like HVAC changes).

Choosing the Right Biosafety Cabinet for Your Needs

Before you make a final decision on which cabinet to purchase, you should carefully consider your research needs.

  • Work Type: Do you require protection for your people, the environment, your product, or a combination of the three?
  • Containment Level: It’s vital to get a biological safety cabinet that can handle the biosafety level (BSL-1 to BSL-4) of the substances you’ll be working with.
  • Lab Space and Configuration: Make sure you have enough space in your laboratory for the cabinet to have a permanent placement.
  • Regulatory Compliance: Make sure you adhere to standards set by OSHA, CDC, and NSF.

A Laboratory Necessity

The biosafety cabinet is an essential tool for any laboratory researching hazardous biological agents. By familiarizing yourself with different cabinet types, biosafety levels, and maintenance requirements, you can make an informed purchase for your lab’s needs. Whether you’re in the market for biosafety cabinets or you have some you need to sell, get in touch with us at BaneBio—the Scientific Supermarket.

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Understanding Lab Closures: A Comprehensive Lab Logistics Guide

empty laboratory filled with equipment in need of lab logistics

Lab logistics are a critical component in the process of closing a lab. Without them, there’s no plan, communication, or organization. And most importantly, you run the risk of unsafe, uncompliant shutdown procedures. A well-planned closure can do wonders for your lab closure process by minimizing risk, protecting the environment, and preserving valuable resources. Do you want to navigate the lab-closure process efficiently and effectively through professional lab logistics solutions? Want to know what to do with all your used lab equipment? First, you need an understanding of everything involved. On top of that, services from the team at BaneBio can go a long way towards a smooth closure. This blog covers everything you need to know!

What’s Involved in a Lab Closure?

There are so many moving parts involved in closing a lab, doing it yourself is likely an insurmountable task. That’s why you want someone like BaneBio at your back, utilizing years of experience and refined lab logistics processes to ensure success. The process we follow is intricate, and is most effective when our customers understand it. So without delay, we’re going to get into the sequence of events that make for a seamless closure.

Planning

Before any equipment is even touched, we take stock of your lab—the equipment you have, the types of substances you work with, and the size of your lab—and come up with an action plan. How will the equipment be disposed of? What codes need to be followed to remain in compliance? What needs to be done with your lease if one exists?

Lab Equipment

Taking care of lab equipment is a large part of the lab closure process. Once we finish inventorying it, we assess its condition. If it doesn’t meet our standards, arrangements will be made to dispose of it in a safe, compliant manner. However, this is a last resort, as we want to avoid producing unnecessary waste. In many cases, equipment in a lab that’s closing is still in full working condition. If it doesn’t quite hit the mark, it gets refurbished. At this point, there are a few options available to you.

  • Sell to BaneBio: We’re happy to buy used lab equipment you no longer need so it can continue to be used in other scientific efforts elsewhere. We will create a purchase proposal and work with you to come to an agreement. Our offer factors in things like the current value of the equipment in the used market, trends in equipment, and our own observations on pieces of equipment and their demand.
  • Give it to Other Labs: There are likely many labs that could make use of the equipment you’re getting rid of. We’ll search for potential takers in the area and arrange the transportation of lab equipment, as well as any other logistics.
  • Donate: Another option is to donate the laboratory equipment to a nearby institution such as a school or museum. 

Lab Space

Once the lab equipment itself is taken care of, there is still plenty to be done to decommission the space. For starters, strict cleaning procedures must be followed. The space has an uncertain future use at this point, and because of this, we need to make sure we don’t leave behind toxic residue of any kind. Every room gets thorough, top-to-bottom sanitization treatment.

The majority of closing labs are on lease, and thus, the owner of the property needs to be involved in the process. It’s up to them to let us know (and make sure we follow) their guidelines for getting the space rent ready, so it’s important that we maintain communication until the job is done.

Key Considerations for Lab Logistics

It doesn’t matter how large or small your lab is. The process of a lab closure has some key considerations that should be at the forefront of your mind when planning. For one, the handling and disposal of hazardous materials should be handled with care in order to comply with environmental regulations. Failure to comply not only puts personnel at risk, but it could result in various legal issues.

New and used lab equipment decontamination—as well as its removal—should be carried out by following industry best practices so as to avoid residual hazards. While compliance is vital, its documentation is equally important in case it needs to be referenced for any reason in the future. Developing a timeline and budget plan can go a long way towards a successful, compliant, and safe decommissioning.

Common Challenges and How to Overcome Them

A lab closure is no small task. Because of this, there are a number of challenges that could rear their ugly heads if you don’t plan properly. Communication can alleviate these risks. Work closely with both your legal and safety teams in order to properly manage people and resources.

There are also concerns around environmental safety to consider. Perform a thorough risk assessment that involves multiple stakeholders, with mitigation strategies and emergency plans in place. Also important in this process is public perception, so it’s important to be publicly transparent. This will go a long way towards gaining trust with all stakeholders.

BaneBio’s Lab Logistics Services Are Here to Help

A lot goes into a lab closure. There are safety, environmental, and operational factors to take into consideration, so it’s important to have a solid plan. While the researchers in a lab are operating in a highly specialized field, they often lack the qualifications or and time to properly close the lab when the time comes. What’s more, our lab logistics services follow your timeline, not the other way around! If you want to cover all your bases, get in touch with us and we’ll provide a smooth decommissioning process.

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How to Choose a Flammable Storage Refrigerator

scientists working with hazardous materials that need flammable storage solutions

Throughout the ages, fire has been both friend and foe to humankind. We need it, and we want it around, but only at specific times and in specific places. The laboratory is one of those places where there’s probably more chance of the unwanted variety than most, given that so much of the work there is done with flammable materials. But unwanted fire isn’t just a concern for laboratories. In medical facilities and industrial settings, the safe storage of flammable materials is equally crucial to preventing accidents and ensuring the well-being of employees. Flammable storage refrigerators are specifically engineered to safely store volatile substances, maintaining controlled environments that minimize risks. In today’s blog, we’ll explore in-depth how to go about choosing the right kind of storage refrigerator for your particular needs.

Key Considerations

Compliance With Regulations

The first step in selecting a refrigerator like this is ensuring compliance with relevant safety regulations. The Occupational Safety and Health Administration (OSHA) and the National Fire Protection Association (NFPA) have set forth guidelines that govern the storage of flammable materials. OSHA requires that flammable liquids be stored in approved containers and cabinets. NFPA provides specific classifications for the storage of flammable liquids, including recommendations on the type of refrigeration unit to use. Understanding these regulations will go a long way toward keeping your facility compliant and keeping potential hazards at bay.

Storage Capacity

Before purchasing a flammable storage refrigerator, assess the volume of flammable materials you need to store. This requires a thorough inventory of your current stock, as well as your best estimate of future needs. Choosing the right size is crucial; a unit that’s too small may be overcrowded, while a unit that’s too big may lead to excessive energy costs. Do your best to find a refrigerator that accommodates your current inventory with room for growth.

Temperature Control

Consistent and reliable temperature control is vital in a storage refrigerator. Flammable materials often require specific temperature ranges to maintain their integrity and prevent dangerous reactions. As such, look for refrigerators that offer precise temperature settings and stable performance, ensuring that your materials are stored safely. Additionally, consider models with built-in temperature alarms that notify you of any fluctuations outside of acceptable ranges.

Explosion-Proof Features

A good flammable storage refrigerator is also an explosion proof refrigerator. This means it will have a spark-free interior and sealed electrical components, to reduce the risk of ignition of whatever flammable material you’re storing inside of it. When selecting a flammable storage refrigerator, then, make sure it’s also an explosion proof refrigerator—meeting the necessary explosion-proof standards to protect against hazards associated with volatile materials.

Durability & Material

Durability is another critical factor in choosing a flammable storage refrigerator. Look for models constructed from sturdy materials that can withstand harsh environments. Corrosion-resistant materials are essential, especially in settings where spills may occur or humidity levels are high. A durable refrigerator will enhance safety and extend the lifespan of your unit.

Additional Features to Look For

When evaluating flammable storage refrigerators, consider additional features that enhance usability and safety:

  • Adjustable Shelving
    Flexible shelving options allow you to customize the interior space to fit different container sizes, maximizing storage efficiency and making the most of your investment.
  • Lockable Doors
    Security is paramount when storing hazardous materials. Lockable doors help prevent unauthorized access, protecting your inventory and potentially even your facility.
  • Alarms and Monitoring Systems
    Advanced refrigerators may include alarm systems that alert you to temperature fluctuations or door openings, providing an added layer of security and peace of mind.

Common Pitfalls to Avoid

When choosing a flammable storage refrigerator, be aware of common mistakes that can lead to safety hazards:

  • Using Standard Refrigerators for Flammable Materials
    A big no-no. Standard refrigerators are not designed to handle the risks associated with flammable materials. Always use a specialized refrigerator for this highly specialized job.
  • Ignoring Certification Labels and Testing
    Due your due diligence. Always check for certification labels that confirm compliance with safety standards. Units that are not certified may pose significant risks.

Keep Fire Where It Belongs: Elsewhere

No matter where it pops up, unwanted fire is, well, unwanted. You can’t keep the world safe, but you can keep your laboratory, medical facility, or industrial space safe. Choosing the right flammable storage refrigerator is crucial for maintaining a safe environment when volatile materials are involved. By considering factors such as regulatory compliance, storage capacity, temperature control, explosion-proof features, and durability, you can make an informed decision that protects your employees and your assets. For tailored advice, make sure you work with suppliers who specialize in such storage solutions. At BaneBio, we’re always ready to provide insights and recommendations to ensure you select the best refrigerator for your needs.

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Exploring the Different Types of Scientists

decorative image showing 3 scientists performing research

In 1953, James Watson and Francis Crick made a discovery that changed the world forever—the structure of DNA, the genetic code that underpins all life. This discovery, often hailed as one of the most important in biology, was made not by just one scientist but by a team of different types of scientists, all from various scientific disciplines. Watson was a biologist, Crick a physicist. Both relied on the X-ray crystallography data provided by Rosalind Franklin, a chemist, to unlock the double-helix structure of DNA. 

This collaboration between biologists, chemists, and physicists highlights not just the incredible diversity within the scientific community, but how each specialization brings its own unique skillset to the task of solving complex problems. Scientists, in their many forms, are constantly working to unravel the mysteries of the universe, each contributing to the larger tapestry of human knowledge. In this blog, we’ll explore the different types of scientists and how each plays a role in advancing our understanding of the world.

The Importance of Scientists: Diversity of Scientific Fields

“Science” is a single word that covers an absurdly large number of distinct specialties. From studying the infinitesimally small world of atoms and molecules to exploring the vast reaches of space, scientists work across a wide spectrum of professional disciplines. Their expertise helps us understand everything from how our bodies function to how the universe operates. While each discipline has its own focus, all scientists share a common goal: to answer questions, solve problems, and improve our understanding of the world. 

What Defines a Scientist?

Simply put, a scientist is someone who seeks to understand the natural world through observation, experimentation, and analysis. Scientists use the scientific method to form hypotheses, conduct experiments, and analyze data in order to draw conclusions that expand human knowledge. Scientific inquiry is constantly evolving, which leads to the emergence of specialized fields. As our understanding of the world deepens, scientists focus on increasingly specific areas of study. This specialization is essential for addressing the complexity of the universe and solving highly specialized problems.

The Different Types of Scientists

Biologists: Studying Living Organisms and Their Environments
Biologists seek to understand life in all its forms, studying everything from individual cells to complex ecosystems. Their work is foundational in fields like medicine, agriculture, and environmental science. Biologists may specialize in areas such as genetics, ecology, or evolutionary biology, each contributing vital insights into the processes that sustain life.

Chemists: Exploring Substances at the Molecular and Atomic Levels
Chemists focus on the composition, properties, and reactions of substances. They examine how different chemicals interact, how new substances are formed, and how these processes can be harnessed for practical applications. Chemists are critical to fields like drug development, materials science, and environmental protection.

Physicists: Investigating the Laws of Nature, from Particles to Pulsars
Physicists delve into the fundamental forces of the universe. From understanding the behavior of subatomic particles to studying the laws of motion, gravity, and spacetime, physicists work to explain the underlying principles that govern everything from gluons to galaxies. Their work can lead directly to new technologies, such as lasers or computers.

Astronomers: Focusing on Celestial Phenomena and the Universe
Astronomers study stars, planets, and other objects in the firmament. Using telescopes and other instruments, they investigate the nature of the universe, the lifecycle of stars, and the potential for life on other planets. Their work not only expands our understanding of the cosmos but also informs space exploration and the development of technology.

Geologists: Examining Earth’s Physical Structure, Processes, and History
Geologists study the composition, structure, and the processes that shape Earth’s surface. By understanding how our planet has evolved, geologists help us predict natural disasters, explore for natural resources, and understand climate change. Their research also plays a role in preserving biodiversity and ensuring sustainable land use.

Specialized Types of Scientists

Marine Biologists: Diving Into the Mysteries of Ocean Life
Marine biologists study organisms living in the world’s oceans. They research everything from plankton to whales, exploring how these creatures interact with their environment and each other. Marine biology is crucial for understanding ocean ecosystems, preserving marine biodiversity, and addressing challenges such as climate change.

Forensic Scientists: Solving Crimes Through Scientific Analysis
Forensic scientists apply scientific methods to criminal investigations. By analyzing physical evidence such as DNA, fingerprints, and blood spatter, they help solve crimes and bring criminals to justice. Forensic scientists often work in law enforcement, applying their expertise in chemistry, biology, and toxicology to identify culprits.

Environmental Scientists: Working to Combat Climate Change and Pollution
Environmental scientists study how human activity impacts the planet’s ecosystems and work to develop solutions for mitigating environmental damage. Their research includes monitoring pollution levels, studying biodiversity, and finding ways to reduce human impact on the environment. 

Medical Scientists: Developing Treatments and Medical Advancements
Medical scientists focus on understanding diseases and finding ways to treat or prevent them. They conduct clinical research, develop vaccines, and test new medications. During the COVID-19 pandemic, for example, virologists, immunologists, and biochemists worked together to develop vaccines that helped bring the virus under control. 

Why Understanding the Different Types of Scientists Matters

Science is rarely a solitary pursuit. Many of the most significant achievements come from collaboration between scientists from different disciplines. For example, the development of the COVID-19 vaccine involved virologists who studied the virus, immunologists who developed vaccines, and biochemists who synthesized the vaccine components. Finally, data scientists analyzed vast amounts of information to ensure the vaccine’s efficacy.

This interdisciplinary approach is not just limited to health-related fields. Projects like space exploration, climate change research, and the development of clean energy technologies require the input of physicists, chemists, engineers, and environmental scientists working together. Understanding the various types of scientists and their specialized knowledge allows us to see the interconnected nature of scientific progress.

How to Become a Scientist

If you’re a high school or college student interested in becoming a scientist, the path depends on the field that interests you the most. Generally speaking, aspiring scientists begin with a strong foundation in mathematics and science, earning a bachelor’s degree in fields such as biology, chemistry, physics, or engineering. Afterward, they can pursue a graduate degree (master’s or Ph.D.) in their chosen specialty. 

Along the way, they’ll engage in research, internships, and hands-on experiences to build your expertise. Many fields, such as medicine and environmental science, also offer opportunities for additional training and certification. Scientists have the opportunity to work in academia, government, industry, or private research organizations. Some may even choose to start their own research firms or work as consultants.

It Takes a Village

From the biologists who explore the complexities of life to the physicists who explore the complexities of the universe, scientists are essential to advancing our knowledge and improving our world. Whether solving global challenges or unraveling the mysteries of the cosmos, scientists’ contributions are indispensable to the progress of society. By understanding the different types of scientists and their areas of expertise, we gain a deeper appreciation for the collaborative and ever-evolving nature of scientific discovery.

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Choosing the Right Centrifuge for Your Laboratory

scientist using a centrifuge

There’s so much lab equipment that does so much essential work for us. Pipettes. Clean benches. Microscopes. Scales. The list goes on. But while it’s all equipment we couldn’t do without, we probably take much of it for granted nonetheless. Add the centrifuge to this not-so-humble list. By using centrifugal force to harness the power of gravity, these machines efficiently and effectively separate components of different densities, enabling scientists and researchers to isolate cells, proteins, nucleic acids, and other materials for further study. As the choice of machine significantly impacts the accuracy of lab procedures, the importance of selecting the right type can’t be overstated. Today, we’ll walk you through the key considerations for choosing a centrifuge machine that offers the perfect range of capabilities for your lab’s work.

Key Considerations

1. Speed (RPM) and G-Force Requirements

Centrifuge speeds are measured in revolutions per minute, or RPM. The faster the spin speed, the more centrifugal force, or g-force, generated. Different laboratory applications call for different spin speeds/g-force. Understanding the requirements for the samples you need to analyze will help you select a machine capable of delivering the appropriate performance.

2. Sample Size and Capacity

The volume of your samples is another critical consideration for selecting the right centrifuge machine. They come in various sizes, each designed to accommodate different sample capacities. Assessing your typical sample sizes will guide you toward the right model.

3. Type of Sample

The nature of the samples being processed is equally important to selecting the right machine. Blood, cells, proteins, and other materials may require different spin speeds and time settings, making it crucial to choose a centrifuge tailored to your lab’s specific needs.

4. Specialized Applications

Certain labs focus on specialized applications, whether clinical, research, or industrial. Take the time to think through all the work your lab does on a regular basis. Understanding those needs will help you select a lab centrifuge that meets its very specific demands.

Common Types of Centrifuges

1. Microcentrifuges

Microcentrifuges are compact machines ideal for handling small-volume samples ranging from 0.2 to 2 mL. They are commonly used for DNA/RNA processing and cell fractionation, making them a staple in molecular biology laboratories.

2. Benchtop Centrifuges

Benchtop centrifuges are versatile and space-saving, suitable for medium-capacity samples in routine lab work. They offer a balance between performance and size, making them a popular choice for a wide range of laboratory settings.

3. High-Speed Centrifuges

A high-speed centrifuge is designed to generate high RPM, making it capable of processing large-volume samples. This kind of machine is particularly useful in biochemistry and molecular biology applications, where separation efficiency is paramount.

4. Ultracentrifuges

As the name suggests, ultracentrifuges operate at ultra-high spin speeds, allowing for the separation of minute particles, such as viruses and proteins. These devices are essential for advanced research applications, where precision and reliability are critical.

5. Refrigerated Centrifuges

Refrigerated centrifuges offer users temperature control, making them suitable for sensitive samples that require specific temperatures. They are commonly used in clinical and biochemistry laboratories, where maintaining sample integrity is crucial.

Choosing the Right Machine for Your Lab

1. Matching the Model to Your Lab’s Needs

Evaluate your lab’s requirements, including sample types, volumes, and the desired outcomes of your experiments. This assessment will help in narrowing down your model options.

2. The Importance of Scalability and Future-Proofing

Consider not only your current needs but also potential future applications. Investing in a centrifuge that offers scalability can save costs and accommodate evolving research demands.

3. Tips on Budget Considerations and Maintenance

Budgeting is an important aspect of selecting laboratory equipment. Ensure you factor in both the initial purchase price and long-term maintenance costs. Additionally, consult with manufacturers about service options to ensure the longevity of your lab centrifuge.

The Right Supplier, the Right Equipment

In the field of science, where so much important work is done on so many levels, it’s unwise to take anything for granted, including the equipment that allows professionals like you to properly carry out their work. As such, choosing the right centrifuge for your laboratory is essential for achieving optimal results across all of your experiments. By understanding the key factors—such as speed, sample size, and application type—you can make an informed decision that will suit your needs now and into the future. BaneBio is always ready to help labs make informed decisions on a wide range of equipment, including centrifuges. Contact us today!

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Lab Water Purification Systems: Ensuring Purity and Precision

laboratory that uses water purification systems

When we drink water at home, most of us are aware that it may not be the world’s purest water. This doesn’t necessarily mean it’s dirty, but tap water has rarely been through high-quality filters. We’re okay with that, and we accept a certain level of “stowaways” in our water. When it comes to laboratory science, however, we don’t have that luxury. Pure water is a necessity, not a preference. Even in trace amounts, contaminants can compromise entire experiments, leading to inaccurate data. That’s why water purification systems are vital to a lab’s operations.

But what exactly do these systems do? How do they work, and why are they so important? Let’s take a closer look.

Understanding Lab Water Purification Systems

There are several different types of water purification systems, each one designed to eliminate specific contaminants and meet the proper purity requirements for research.

  • Reverse Osmosis (RO): With this system, water is forced through a semipermeable membrane, which filters out impurities like ions, particles, and large molecules. RO is ideal for providing water that meets most general laboratory standards.
  • Deionization (DI): Often used in combination with other purification processes, this uses ion-exchange resin to remove dissolved ions from the water. This produces very pure water that is required for sensitive applications.
  • Ultrapure Water Systems: These systems are designed to remove ultra small contaminants from the water. These contaminants include organic compounds, bacteria, and endotoxins. Water of this purity level is vital for processes like molecular biology or mass spectrometry.

How These Systems Work

That’s what they do, but how do they actually work? RO systems rely on pressure to push water through the membranes, which trap the impurities. DI systems, however, use resins to replace ions with hydrogen and hydroxide. The combination of these two forms pure water. As for ultrapure systems, they can incorporate either of these techniques, but also implement additional filters—such as IV sterilization—to maximize water purity.

Key Benefits of Using Water Purification Systems in Labs

Water purification systems can provide several benefits to your experiments, safety, and expenses.

Precision in Experiments

Water purity has a direct correlation with the accuracy and reproducibility of experimental results. Since contaminants can interfere with reactions, skew measurements, and introduce unwelcome variables, maximum purity is essential. Otherwise, the integrity of your data and its consistency could be compromised.

Safety and Compliance

Laboratories are subject to some of the strictest regulatory standards in the world. These standards often dictate the acceptable levels of contaminants in experiments. These regulations are in place to protect the well-being of lab personnel and the general public, as hazardous materials are often used in lab environments. Contaminated water can pose serious risks when interacting with these materials.

Cost Efficiency

A high-quality lab water purification system may carry a hefty up-front price tag, but the overall savings that result from it are worth the investment. Contaminated water can damage sensitive equipment, which could result in costly repairs over time. In addition to that, high chances of invalid experiments have the potential to waste resources and time. Pure water will help you avoid these issues and maximize efficiency.

Choosing the Right Water Purification System

There are several factors that will determine your choice in purification systems.

  • Quality of Water Required: This is likely the most important factor for most people. Ultrapure water is essential for sensitive applications, while RO or DI will work for more general applications.
  • Volume Needs: How much purified water does your lab use on a daily basis? Be sure to factor this in and choose a purification system that can handle the proper output.
  • Specific Lab Applications: It’s important to tailor the system to your lab’s needs. For example, certain labs require more filtration stages or customized features depending on the goals of the research.

Customization Options

If you want to further customize your lab water purification system—research needs are diverse, after all—there are plenty of options to do so. Modular designs, advanced monitoring systems, and integration with existing infrastructure are within the realm of possibility. This level of customization ensures your system will meet purity requirements and align with your workflows.

Conclusion

The pursuit of scientific excellence is what drives much innovation. The proper equipment—including water purification systems—is vital to its success. From maximizing safety to improving the accuracy of results, purified water plays a foundational role in good scientific practice. For further assistance or advice on these vital systems, get in touch with us at BaneBio. We’ll be happy to help!

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Choosing the Right Microscopes for Your Laboratory

scientist using microscopes to perform research

Microscopes are a powerful and widely used tool in the biotech industry. Selecting the right types of microscopes for your research is crucial.  Let’s take a look at steps to take and what to consider before pulling the trigger on pricey (but essential) equipment for your lab.

Understanding Your Requirements

These days, there’s a microscope designed for everything. Only you know the specific use case in your lab, use that knowledge to inform your purchasing decision. If you want to share your vision with us, we can help you along the way.

  • Primary Purpose: Here’s a good starting question: What purpose will the devices serve in your lab? Will they be used for teaching, quality control, diagnostics, or something else? What kinds of specimens will you be observing?
  • Determining Sample Types: Depending on the kinds of samples your research will focus on, you could need specific equipment. Consider what you’ll be examining frequently. Will they be biological specimens, chemicals, or solid materials?
  • Budget Considerations: Of course, you can’t just select the most high-end equipment without regard to your budget. Keep in mind that in addition to the initial cost of a microscope, there’s potential for future maintenance and upgrades. Striking a balance between price and quality is tricky, for sure, but worth it.

Types of Microscopes

Just like you wouldn’t use a paring knife to butcher a chicken, you’re not going to be able to examine a nanocrystal very well with an optical microscope. To determine the best application for different kinds of research, let’s put the different options—well—under the microscope!

  • Upright/Compound: One of the most common types, this is used in most labs and other scientific settings to view blood cells, parasites, bacteria, cheek cells, and other similar samples.
  • Inverted: This device offers magnification ranging anywhere from 40x–400x, and is typically used to view living samples, tissues, and cells in a petri dish. It’s perfect for cell biology, neuroscience, and microbiology!
  • Stereo/Dissecting: Typically providing 10x–40x magnification, this equipment is used to observe things you can hold in your hand, like a penny or small animal for dissection. It is often used for samples that don’t allow light to pass through them.
  • Fluorescence: This uses high-intensity light instead of visible light to examine specimens that have been stained with a fluorescent dye, presenting a bright image set against a dark background. This is an ideal instrument for ecological studies as well as live versus dead bacteria.
  • Digital: Rather than mirrors and lenses, this uses a digital camera to display its images on a digital screen. This allows for easy viewing, recording, and image analysis. Additionally, it generally includes software that helps with measurements, annotation, and image processing. This makes it perfect for general use in both research and educational environments.
  • Phase Contrast: This enhances the contrast of transparent and colorless specimens, making them visible without the need for staining. This is achieved by exploiting differences in the refractive index of different parts of the specimen, converting subtle phase shifts in light passing through the specimen into variations in light intensity that can be observed. This instrument is ideal for live-cell imaging, cell culture studies, and detailed biological sample examinations.

Matching Features with Your Needs

You’ve considered your needs to determine the type of microscope you’ll need, but there’s still more work to be done. Depending on the model you get, they can come with several different features and capabilities. 

  • Magnification and Resolution: Generally, high magnification means higher cost. Keeping this in mind, you probably don’t need the highest magnification capabilities if you’re working with cellular structures.
  • Illumination Options: Light can play a key role in the quality of the images you obtain. The differences between LED and halogen could be vast, for example.
  • Imaging and Digital Capabilities: Today’s devices have plenty of imaging capabilities that allow for the capture and sharing of images. These features are helpful if you’re collaborating or preparing a presentation.
  • Ergonomics and User-Friendliness: No equipment is fun to use if it’s uncomfortable. If the design of something is at odds with the physical build of its user, research will be much more difficult.

Considering Scalability

Do you plan on expanding your lab and research capabilities? If so, it’s good to keep those plans in mind when buying your equipment. After all, renovations and other supplies are costly enough. Wouldn’t it be great to keep your existing tools rather than require all new ones?

Before you buy, explore the possibilities of add-ons and accessories that are compatible with any purchase you’re considering. A tool with great out-of-the-box features may be useless when your lab’s objectives evolve.

Do Your Research

Nobody likes discovering their purchase is falling short of their expectations. This is where careful research can save you that headache altogether! Here are a few things to consider:

  • Research Brands and Manufacturers: There’s a reason manufacturers like Zeiss and Olympus have been around for decades. It’s because they make good products! Take some time to research brands and their track records before clicking the “Buy” button.
  • Compare Warranties and Support: A robust warranty can be a dealmaker in your search for laboratory tools. Support like BaneBio provides for our customers is next to none.
  • Look up Product Reviews: You probably looked at the reviews before your most recent Amazon purchase, so why not do the same with your microscope? 

Conclusion

A good laboratory manager will know the lab’s goals and work scope before carelessly purchasing equipment. By understanding your own requirements, types of equipment, and manufacturer options, you can make purchases that will benefit your scientific work for years to come.

Still need a little help making your decision? That’s alright. We’re happy to help you make your decision! Or if you’re simply curious about our microscopes for sale, feel free to take a look. Let’s make your lab the best it can be!

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Choosing the Right Equipment for Your Lab

glass lab equipment sitting on a counter

Scientific work can’t thrive without the proper equipment. It directly impacts work quality and efficiency, as well as safety. With the right tools, you can achieve optimal research outcomes, streamline your workflows, and maintain safety for all lab personnel. With that in mind, let’s go over what to consider when crafting your laboratory equipment list.

Key Considerations for Choosing Common Lab Equipment

No matter what you’re buying or who you’re buying from, making a purchase without a plan is likely to come back and bite you. With that said, let’s go over a few things to consider before buying.

Understanding Your Needs

To start, take stock of the needs of your lab. What type of research do you conduct? What samples do you work with, and what volume do you handle on a daily basis? Different fields and samples may require special equipment, so assessing those needs is crucial to making smart purchases.

Additionally, you have to keep available lab space in mind. While it would be great to fit all the best equipment into your lab, sometimes square footage limits what you can bring in. The supplies you choose should fit comfortably in your space, while still allowing you room to move around and conduct research. Measure the available space within your lab and keep it top of mind so you can optimize while shopping (we can help with that).

Evaluating Performance and Features

Capacity, throughput, and precision are all important factors in determining how effective a piece of equipment will be. After all, if it can’t handle your workload, it’s not worth purchasing. Analyze these performance points thoroughly to ensure they meet your standards.

But those things aren’t all you should keep in mind. Any workplace is destined to fail if safety isn’t a priority, and that’s especially true of a laboratory where you’ll be experimenting, testing, and analyzing. No item on your laboratory equipment list should have a poor safety rating. Make sure it complies with regulations and standards.

Budget and Long-Term Value

Before clicking “purchase” on your laboratory equipment list items, ask yourself: “Will this benefit me in the long-run?” If the answer is “no,” you should look for something better suited to your needs. The up-front cost of most pieces of equipment is an investment, so having confidence that it will pay itself off is crucial to your lab’s success.

It isn’t just the initial fee that you should factor in, though. Even the best equipment will require maintenance from time to time, and maintenance means money. Opting for a tool that is reliable and requires minimal maintenance is key to its longevity and that of your funds. Another thing that could keep your costs low is energy usage. If a microscope you’ve had your eye on requires a small power plant to run, you should probably look elsewhere.

Future-Proofing Your Lab

Making sure your equipment lasts is an important consideration, but it’s about more than that. Will it remain useful if your lab expands and your operations grow? Where does it fit in if you implement all new research methods? The scalability and upgradability of the things you use day to day and year to year are a crucial aspect of any growing lab, so craft your lab equipment list with that in mind.

Best Practices for Selecting and Using Lab Equipment

Not all equipment is created equally. If it were, we wouldn’t have nearly as many options (because what would be the point?). That’s why you should do proper research when crafting your laboratory equipment list. 

Research and Comparison

Read reviews and compare features across different brands and models. These, along with any peer recommendations you can solicit, will give you great insights on the real-world performance and reliability of the equipment you’re considering. If you have any questions on choosing the best option for you, we’re always happy to help you out!

Engaging with Suppliers

If you get your information straight from the experts who want you to succeed, you’re more likely to get accurate information on your potential purchases. Engage directly with the suppliers for detailed specifications and features, and request a demo so you can see the tools in action.

What’s even more valuable than a company who makes a good product is one that offers quality post-purchase support as well. When you have competent people helping you troubleshoot, the road to a resolution will be a short one.

Maintenance and Calibration

As we discussed before, routine maintenance and calibration are crucial for keeping everything in great condition. Setting a consistent schedule rather than waiting until you experience a breakdown will save you loads of trouble throughout the lifetime of your equipment.

That said, the less troubleshooting you have to do, the better. Proper cleaning and upkeep can go a long way towards ensuring optimal performance of any item on your laboratory equipment list. Just be sure to follow the manufacturer’s guidelines so you don’t accidentally cause damage.

Safety and Efficiency Tips

Have we mentioned that safety is important? Well, we’re going to harp on it again, because it should be mandatory in any lab. When it comes to your equipment, establishing solid lab safety rules for both operation and maintenance means your lab personnel are protected.

As for actually using the equipment, a well-trained staff could increase productivity and efficiency tenfold. Make sure they’re all on the same page in terms of best practices, cleaning, and of course, safety.

Conclusion

Building an ideal laboratory equipment list is no small feat, but it’s worth it. By analyzing your needs, doing proper research, setting a maintenance schedule, and establishing lab safety rules, you can make great purchases and get the most out of them for years to come.

If you’re wondering where you can find the largest selection of laboratory equipment from all the big brands, look no further than BaneBio. They call us the Scientific Supermarket for good reason. We even have an Ebay store, if you want to see our full stock. So reach out and let’s get your laboratory properly outfitted!

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QuantStudio: Revolutionizing qPCR Machines and PCR Systems

Quantstudio for qPCR and PCR machines

It’s hard to overstate the importance of reliable equipment in the world of molecular biology. When precision is such a key component, bad equipment just won’t cut it. Thankfully, the QuantStudio equipment line is leading the charge in high performance equipment. Developed by Thermo Fisher Scientific, it offers the precision and efficiency that’s required in the field. Let’s take a deep dive into this revolutionary set of instruments, and how it’s pushing forward qPCR machines and PCR systems.

Understanding the Basics of qPCR Machines

For the uninitiated, quantitative PCR (qPCR) is the technique of amplifying and quantifying a targeted DNA molecule. The purpose? To allow researchers to measure the amount of DNA in a given sample. This makes the tool essential in multiple applications, from pathogen detection to gene expression analysis.

These qPCR machines use top-of-the-line optics and thermal technology to give reproducible, accurate results. They use fluorescent dyes to monitor the process of amplification in real time, which yields data that’s invaluable in scientific investigations.

Exploring PCR Systems

Ready to dive further into these systems? There’s a lot to learn, starting with Polymerase Chain Reaction (PCR) systems. They’re the bread and butter of molecular biology research, allowing DNA sequences to be amplified to generate countless copies (think millions) of a targeted segment. Depending on your goals and procedures, there are a few different kinds of systems available: Standard, digital, and qPCR, which we’ve already discussed.

We know QuantStudio specifically plays a vital role in the progress of PCR systems, but how exactly does it do it? It integrates technologies that enhance sensitivity, throughput, and specificity, making it a powerful tool for several applications. This means researchers can achieve a diverse range of scientific goals with accuracy.

Key Features

This equipment offers a plethora of features that make it the new gold standard in comparison to other PCR and qPCR systems. Let’s go over a few of them!

  • High Sensitivity and Precision: These instruments can detect incredibly small quantities of DNA, which ensures proper quantification every time.
  • User-Friendly Interface: State-of-the-art software and a user-friendly interface make for a small learning curve when it comes to running experiments.
  • Multiplexing Capabilities: Time and sample consumption can be significantly reduced thanks to the ability to analyze multiple targets in a single reaction.
  • Flexible Formats: Various formats are available in order to accommodate various throughput needs, ranging from single-tube assays to 384-well plates. 

Similarly, it offers impressive performance compared to similar available qPCR and PCR systems. Reviews and case studies shed more light on the effectiveness of this equipment in a range of research settings. 

Applications and Use Cases

QuantStudio systems are incredibly versatile. Here are come of the field they’re frequently used in:

  • Research: Used in industrial research labs for things like genotyping and gene expression studies, among several others.
  • Clinical Diagnostics: High precision makes it perfect for diagnostic applications like disease detection and genetic disorders.
  • Agricultural and Food Safety: Ensures food quality thanks to the ability to detect pathogens and test GMOs.

As an example, QuantStudio has been used to streamline gene expression analyses, which resulted in faster, more accurate data.

Choosing the Right Model

Thermo Fisher Scientific has several models of this system on offer. Each one is designed for application in specific research scenarios. They vary in terms of capabilities, so let’s take a look at what you should keep in mind when making your selection.

  • Throughput: Determine how many samples need to be processed for each run.
  • Sensitivity: Select a model that boasts the right sensitivity for the assays you’re working with. 
  • Budget and Resources: Determine the cost-effectiveness as well as the resources available. It’s important to be able to purchase and maintain this equipment.

Conclusion

The impressive features and performance offered by these systems make them an essential part of any lab. By integrating them into your research, you’ll see an increase in precision and efficiency you never thought possible.

Following operation and maintenance best practices is essential for the performance and longevity of your QuantStudio Equipment. Luckily, our professionals know it like the backs of their hands and are available to provide service and pointers! Get in touch with us for all your QuantStudio questions and needs!