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Choosing the Right Centrifuge for Your Laboratory

scientist using a centrifuge

There’s so much lab equipment that does so much essential work for us. Pipettes. Clean benches. Microscopes. Scales. The list goes on. But while it’s all equipment we couldn’t do without, we probably take much of it for granted nonetheless. Add the centrifuge to this not-so-humble list. By using centrifugal force to harness the power of gravity, these machines efficiently and effectively separate components of different densities, enabling scientists and researchers to isolate cells, proteins, nucleic acids, and other materials for further study. As the choice of machine significantly impacts the accuracy of lab procedures, the importance of selecting the right type can’t be overstated. Today, we’ll walk you through the key considerations for choosing a centrifuge machine that offers the perfect range of capabilities for your lab’s work.

Key Considerations

1. Speed (RPM) and G-Force Requirements

Centrifuge speeds are measured in revolutions per minute, or RPM. The faster the spin speed, the more centrifugal force, or g-force, generated. Different laboratory applications call for different spin speeds/g-force. Understanding the requirements for the samples you need to analyze will help you select a machine capable of delivering the appropriate performance.

2. Sample Size and Capacity

The volume of your samples is another critical consideration for selecting the right centrifuge machine. They come in various sizes, each designed to accommodate different sample capacities. Assessing your typical sample sizes will guide you toward the right model.

3. Type of Sample

The nature of the samples being processed is equally important to selecting the right machine. Blood, cells, proteins, and other materials may require different spin speeds and time settings, making it crucial to choose a centrifuge tailored to your lab’s specific needs.

4. Specialized Applications

Certain labs focus on specialized applications, whether clinical, research, or industrial. Take the time to think through all the work your lab does on a regular basis. Understanding those needs will help you select a lab centrifuge that meets its very specific demands.

Common Types of Centrifuges

1. Microcentrifuges

Microcentrifuges are compact machines ideal for handling small-volume samples ranging from 0.2 to 2 mL. They are commonly used for DNA/RNA processing and cell fractionation, making them a staple in molecular biology laboratories.

2. Benchtop Centrifuges

Benchtop centrifuges are versatile and space-saving, suitable for medium-capacity samples in routine lab work. They offer a balance between performance and size, making them a popular choice for a wide range of laboratory settings.

3. High-Speed Centrifuges

A high-speed centrifuge is designed to generate high RPM, making it capable of processing large-volume samples. This kind of machine is particularly useful in biochemistry and molecular biology applications, where separation efficiency is paramount.

4. Ultracentrifuges

As the name suggests, ultracentrifuges operate at ultra-high spin speeds, allowing for the separation of minute particles, such as viruses and proteins. These devices are essential for advanced research applications, where precision and reliability are critical.

5. Refrigerated Centrifuges

Refrigerated centrifuges offer users temperature control, making them suitable for sensitive samples that require specific temperatures. They are commonly used in clinical and biochemistry laboratories, where maintaining sample integrity is crucial.

Choosing the Right Machine for Your Lab

1. Matching the Model to Your Lab’s Needs

Evaluate your lab’s requirements, including sample types, volumes, and the desired outcomes of your experiments. This assessment will help in narrowing down your model options.

2. The Importance of Scalability and Future-Proofing

Consider not only your current needs but also potential future applications. Investing in a centrifuge that offers scalability can save costs and accommodate evolving research demands.

3. Tips on Budget Considerations and Maintenance

Budgeting is an important aspect of selecting laboratory equipment. Ensure you factor in both the initial purchase price and long-term maintenance costs. Additionally, consult with manufacturers about service options to ensure the longevity of your lab centrifuge.

The Right Supplier, the Right Equipment

In the field of science, where so much important work is done on so many levels, it’s unwise to take anything for granted, including the equipment that allows professionals like you to properly carry out their work. As such, choosing the right centrifuge for your laboratory is essential for achieving optimal results across all of your experiments. By understanding the key factors—such as speed, sample size, and application type—you can make an informed decision that will suit your needs now and into the future. BaneBio is always ready to help labs make informed decisions on a wide range of equipment, including centrifuges. Contact us today!

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Choosing the Right Equipment for Your Lab

glass lab equipment sitting on a counter

Scientific work can’t thrive without the proper equipment. It directly impacts work quality and efficiency, as well as safety. With the right tools, you can achieve optimal research outcomes, streamline your workflows, and maintain safety for all lab personnel. With that in mind, let’s go over what to consider when crafting your laboratory equipment list.

Key Considerations for Choosing Common Lab Equipment

No matter what you’re buying or who you’re buying from, making a purchase without a plan is likely to come back and bite you. With that said, let’s go over a few things to consider before buying.

Understanding Your Needs

To start, take stock of the needs of your lab. What type of research do you conduct? What samples do you work with, and what volume do you handle on a daily basis? Different fields and samples may require special equipment, so assessing those needs is crucial to making smart purchases.

Additionally, you have to keep available lab space in mind. While it would be great to fit all the best equipment into your lab, sometimes square footage limits what you can bring in. The supplies you choose should fit comfortably in your space, while still allowing you room to move around and conduct research. Measure the available space within your lab and keep it top of mind so you can optimize while shopping (we can help with that).

Evaluating Performance and Features

Capacity, throughput, and precision are all important factors in determining how effective a piece of equipment will be. After all, if it can’t handle your workload, it’s not worth purchasing. Analyze these performance points thoroughly to ensure they meet your standards.

But those things aren’t all you should keep in mind. Any workplace is destined to fail if safety isn’t a priority, and that’s especially true of a laboratory where you’ll be experimenting, testing, and analyzing. No item on your laboratory equipment list should have a poor safety rating. Make sure it complies with regulations and standards.

Budget and Long-Term Value

Before clicking “purchase” on your laboratory equipment list items, ask yourself: “Will this benefit me in the long-run?” If the answer is “no,” you should look for something better suited to your needs. The up-front cost of most pieces of equipment is an investment, so having confidence that it will pay itself off is crucial to your lab’s success.

It isn’t just the initial fee that you should factor in, though. Even the best equipment will require maintenance from time to time, and maintenance means money. Opting for a tool that is reliable and requires minimal maintenance is key to its longevity and that of your funds. Another thing that could keep your costs low is energy usage. If a microscope you’ve had your eye on requires a small power plant to run, you should probably look elsewhere.

Future-Proofing Your Lab

Making sure your equipment lasts is an important consideration, but it’s about more than that. Will it remain useful if your lab expands and your operations grow? Where does it fit in if you implement all new research methods? The scalability and upgradability of the things you use day to day and year to year are a crucial aspect of any growing lab, so craft your lab equipment list with that in mind.

Best Practices for Selecting and Using Lab Equipment

Not all equipment is created equally. If it were, we wouldn’t have nearly as many options (because what would be the point?). That’s why you should do proper research when crafting your laboratory equipment list. 

Research and Comparison

Read reviews and compare features across different brands and models. These, along with any peer recommendations you can solicit, will give you great insights on the real-world performance and reliability of the equipment you’re considering. If you have any questions on choosing the best option for you, we’re always happy to help you out!

Engaging with Suppliers

If you get your information straight from the experts who want you to succeed, you’re more likely to get accurate information on your potential purchases. Engage directly with the suppliers for detailed specifications and features, and request a demo so you can see the tools in action.

What’s even more valuable than a company who makes a good product is one that offers quality post-purchase support as well. When you have competent people helping you troubleshoot, the road to a resolution will be a short one.

Maintenance and Calibration

As we discussed before, routine maintenance and calibration are crucial for keeping everything in great condition. Setting a consistent schedule rather than waiting until you experience a breakdown will save you loads of trouble throughout the lifetime of your equipment.

That said, the less troubleshooting you have to do, the better. Proper cleaning and upkeep can go a long way towards ensuring optimal performance of any item on your laboratory equipment list. Just be sure to follow the manufacturer’s guidelines so you don’t accidentally cause damage.

Safety and Efficiency Tips

Have we mentioned that safety is important? Well, we’re going to harp on it again, because it should be mandatory in any lab. When it comes to your equipment, establishing solid lab safety rules for both operation and maintenance means your lab personnel are protected.

As for actually using the equipment, a well-trained staff could increase productivity and efficiency tenfold. Make sure they’re all on the same page in terms of best practices, cleaning, and of course, safety.

Conclusion

Building an ideal laboratory equipment list is no small feat, but it’s worth it. By analyzing your needs, doing proper research, setting a maintenance schedule, and establishing lab safety rules, you can make great purchases and get the most out of them for years to come.

If you’re wondering where you can find the largest selection of laboratory equipment from all the big brands, look no further than BaneBio. They call us the Scientific Supermarket for good reason. We even have an Ebay store, if you want to see our full stock. So reach out and let’s get your laboratory properly outfitted!

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QuantStudio: Revolutionizing qPCR Machines and PCR Systems

Quantstudio for qPCR and PCR machines

It’s hard to overstate the importance of reliable equipment in the world of molecular biology. When precision is such a key component, bad equipment just won’t cut it. Thankfully, the QuantStudio equipment line is leading the charge in high performance equipment. Developed by Thermo Fisher Scientific, it offers the precision and efficiency that’s required in the field. Let’s take a deep dive into this revolutionary set of instruments, and how it’s pushing forward qPCR machines and PCR systems.

Understanding the Basics of qPCR Machines

For the uninitiated, quantitative PCR (qPCR) is the technique of amplifying and quantifying a targeted DNA molecule. The purpose? To allow researchers to measure the amount of DNA in a given sample. This makes the tool essential in multiple applications, from pathogen detection to gene expression analysis.

These qPCR machines use top-of-the-line optics and thermal technology to give reproducible, accurate results. They use fluorescent dyes to monitor the process of amplification in real time, which yields data that’s invaluable in scientific investigations.

Exploring PCR Systems

Ready to dive further into these systems? There’s a lot to learn, starting with Polymerase Chain Reaction (PCR) systems. They’re the bread and butter of molecular biology research, allowing DNA sequences to be amplified to generate countless copies (think millions) of a targeted segment. Depending on your goals and procedures, there are a few different kinds of systems available: Standard, digital, and qPCR, which we’ve already discussed.

We know QuantStudio specifically plays a vital role in the progress of PCR systems, but how exactly does it do it? It integrates technologies that enhance sensitivity, throughput, and specificity, making it a powerful tool for several applications. This means researchers can achieve a diverse range of scientific goals with accuracy.

Key Features

This equipment offers a plethora of features that make it the new gold standard in comparison to other PCR and qPCR systems. Let’s go over a few of them!

  • High Sensitivity and Precision: These instruments can detect incredibly small quantities of DNA, which ensures proper quantification every time.
  • User-Friendly Interface: State-of-the-art software and a user-friendly interface make for a small learning curve when it comes to running experiments.
  • Multiplexing Capabilities: Time and sample consumption can be significantly reduced thanks to the ability to analyze multiple targets in a single reaction.
  • Flexible Formats: Various formats are available in order to accommodate various throughput needs, ranging from single-tube assays to 384-well plates. 

Similarly, it offers impressive performance compared to similar available qPCR and PCR systems. Reviews and case studies shed more light on the effectiveness of this equipment in a range of research settings. 

Applications and Use Cases

QuantStudio systems are incredibly versatile. Here are come of the field they’re frequently used in:

  • Research: Used in industrial research labs for things like genotyping and gene expression studies, among several others.
  • Clinical Diagnostics: High precision makes it perfect for diagnostic applications like disease detection and genetic disorders.
  • Agricultural and Food Safety: Ensures food quality thanks to the ability to detect pathogens and test GMOs.

As an example, QuantStudio has been used to streamline gene expression analyses, which resulted in faster, more accurate data.

Choosing the Right Model

Thermo Fisher Scientific has several models of this system on offer. Each one is designed for application in specific research scenarios. They vary in terms of capabilities, so let’s take a look at what you should keep in mind when making your selection.

  • Throughput: Determine how many samples need to be processed for each run.
  • Sensitivity: Select a model that boasts the right sensitivity for the assays you’re working with. 
  • Budget and Resources: Determine the cost-effectiveness as well as the resources available. It’s important to be able to purchase and maintain this equipment.

Conclusion

The impressive features and performance offered by these systems make them an essential part of any lab. By integrating them into your research, you’ll see an increase in precision and efficiency you never thought possible.

Following operation and maintenance best practices is essential for the performance and longevity of your QuantStudio Equipment. Luckily, our professionals know it like the backs of their hands and are available to provide service and pointers! Get in touch with us for all your QuantStudio questions and needs!

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Used Lab Equipment for Your Lab

autoclave sterilizing equipment

What’s the first thing that comes to mind when you hear the word “laboratory?” It’s probably a microscope, and for good reason. It’s an essential piece of equipment in a lab setting. There are plenty of other pieces of equipment that hold a similar level of importance when it comes to research. Without them, many aspects of science would be unable to advance. Even the brightest minds need them for their research. Your lab may be on a tight budget, but you have to have these machines and gadgets. That’s where used lab equipment comes in!

Benefits of Buying Used Lab Equipment

One of the most significant advantages of opting for used equipment is the cost savings. Equipment that’s fresh off the production line can have sky-high price tags that either strain your budget or exceed it entirely. If it’s used, it can be acquired at a better price point.

Of course, used products always come with the uncertainty of whether or not they’ll work. At BaneBio, our quality control and testing process is second to none. If it doesn’t meet the original specs and offer excellent performance and longevity, we don’t list it for sale.

As if those incentives weren’t enough, buying used helps the environment! By purchasing second-hand, you’re trimming down electronic waste and promoting an attitude of sustainability in yourself and your lab. With sustainability becoming a prominent talking point in pretty much every industry, eco-friendly practices like this contribute to global green initiatives!

Key Considerations When Purchasing Lab Equipment

Just because we guarantee the quality of our used equipment, that doesn’t mean every seller follows suit. If you’re shopping around, here are a few things to keep in mind. 

  • Equipment Condition: No matter who you’re buying from, always check the condition of the equipment. 
  • Seller Credibility: Even if a piece of equipment looks like it’s in pristine condition, don’t buy without doing research on the seller. Reputable ones will give you detailed information and records about the used lab equipment you’re considering.
  • Warranties or Guarantees: These are essential when it comes to used equipment of any kind. It’s disheartening enough when something breaks. It’s even worse when you can’t get your money back for it.

Types of Used Lab Equipment

We all know about the microscope. It gets all the attention, but we want to go over the unsung heroes of the laboratory. Without them, you probably won’t get far in some of your research projects.

Autoclaves

These are essential for sterilizing your equipment and materials. Because of their use of high pressure steam, viruses and bacteria run in fear from them. That said, there are different autoclave types that are specialized according to sterilization needs. These types range from gravity displacement, pre-vacuum, and steam generator.

When you’re purchasing an autoclave, here are a few factors to keep in mind to make sure you make the right call.

  • Size: Can the autoclave you have your eye on handle the kind of sterilization your lab requires?
  • Cycle Time: Look for models that offer efficient cycle times so you can maximize your productivity.
  • Temperature Range: Can it reach the temperatures required to meet your sterilization needs?

Ultrasonic Cleaners

These are similar to autoclaves in that they’re used to clean equipment. However, the difference comes in the method. An ultrasonic cleaner gets the job done with high-frequency sound waves that can remove contaminants from complex and delicate surfaces. They’re fast and efficient, and they require minimal manual intervention.

If you’re in the market for one of these essential cleaning tools, consider these factors:

  • Frequency: If you have delicate items, aim for high frequency. Need more robust cleaning done? Lower frequency is up to the task.
  • Capacity: Make sure the tank in the ultrasonic cleaner is large enough to handle your average cleaning load.
  • Power Output: The higher the power output, the more efficient. This may not be necessary for the less complex equipment, however.

Incubators

If you’re dealing with microbial and cell cultures in any way, an incubator is essential for cultivation. CO2 incubators are ideal for cell culture, while refrigerated ones are used for low temperature storage and experimentation.

When you’re trying to make a decision on a used incubator, consider these:

  • Temperature Control: Accurate temperature control is a must in any incubator.
  • Humidity Levels: Depending on the application, you may need precise humidity control.
  • Interior Space: Does the model you’re considering offer enough space for your samples?

We’re the Supermarket for Your Used Lab Equipment!

Purchasing used lab equipment can be a boon for your laboratory. Between the cost savings, quality assurance, and other benefits we offer, it’s well worth your consideration over the shiny new stuff. By considering things like condition, seller credibility, and warranties (areas we excel in), you can get your hands on high quality equipment and save money doing it! 

Are you ready to outfit your lab with top-quality tools? Reach out to BaneBio at the scientific supermarket and enhance your research!

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The Essential Modern Lab Equipment List

scientist looking through a microscope

When performing scientific research, different types of laboratory equipment are needed to conduct experiments and analyze information correctly. They help you collect data, measure substances, and observe changes in a controlled environment. 

One tool that we are all likely familiar with is the microscope. Many scientific fields require the ability to see tiny details that aren’t visible to the naked eye. Another tool, a balance, helps to measure the exact mass of a substance. Along with other pieces of common lab equipment, these tools make it possible for scientists to standardize procedures with consistent experimental methods. This allows them to conduct experiments with the confidence that other researchers will follow the same procedures and achieve the same outcomes. By using the same tools and techniques, scientists can compare their findings with others and build upon existing knowledge in the field. This consistency in scientific methods also reduces the margin of error and increases the reliability of the research outcomes.

But what would happen in the same kind of lab if it didn’t have any of the common lab equipment needed for conducting experiments? Well, if there weren’t any microscopes, scientists wouldn’t be able to observe tiny microorganisms, limiting their ability to study cells or bacteria. Also, without the proper tools like balances or pH meters, researchers may not be able to accurately measure substances, affecting the validity of their findings. A lack of proper laboratory equipment could also compromise a lab’s safety, increasing the risk of accidents. Without the proper tools to get the job done, the scene in the lab would become chaotic, progress couldn’t continue, and few to no discoveries would be made. 

Basic Laboratory Equipment 

Every lab should at least have these pieces of laboratory equipment:

  • Microscopes to allow the examination of tiny cells and molecules
  • Centrifuges that spin samples to separate components
  • PH meters to measure how acidic or basic a solution is
  • Balances to give you an ingredient’s exact mass or to compare the masses of two ingredients
  • Incubators for keeping bacteria and cells at optimal and consistent  temperatures

Scientists need the items on this lab equipment list in order to perform research and continue discovering new things about our world. At BaneBio, we’re here to help you set up or upgrade your lab. 

Advanced Equipment for Specialized Research

Now, let’s talk about some advanced scientific tools that are needed for research: 

  • Spectrophotometers measure light absorption and transmission for analyzing chemical composition. 
  • NMR spectrometers look at the core of atoms, studying atomic nuclei’s magnetic properties to show molecular structures and interactions. 
  • Mass spectrometers are used when analyzing the mass characteristics of ions to provide information about the composition and structure of compounds.
  • Chromatography systems separate the molecules within complex mixtures, like the sorting hat in Harry Potter.
  • Polymerase Chain Reaction (PCR) machines act as copy machines for DNA, creating millions of copies in a matter of seconds.

At BaneBio we have the advanced tools that are essential for your high-level scientific research.

Safety Equipment

In the lab, it’s important to have a safety-first policy. Every lab should have fume hoods designed to protect people from toxic fumes. Safety goggles are needed to shield your eyes from chemicals that may splash or be spilled. Emergency showers and eyewash stations can provide quick decontamination. Meanwhile, personal protective equipment (PPE) like gloves and masks provide a barrier to protect you from harmful substances. Of course, a lab also needs fire extinguishers in case there’s a mishap with a Bunsen burner. 

Automation and Robotics

Now, it’s time to think about technology. Liquid handling robots, high-throughput screening systems, and automated sample preparation systems are changing how experiments are done. Liquid handling robots take the repetitive pipetting tasks off your hands. Automation including high-throughput screening systems speed up the discovery of new drugs by screening thousands of compounds at the same time. By assigning mundane tasks to these automated systems, scientists can free up their valuable time for more engaging and intellectually stimulating tasks.

Maintenance and Calibration

Last but not least, maintenance and calibration both matter. Regular maintenance tasks, like cleaning and calibrating lab equipment help instruments stay in good shape. So, don’t skip simple maintenance tasks.

In a science lab, calibration tools can vary depending on the instruments being used. Some of our commonly used calibration tools include:

  1. Calibration weights for balances and scales
  2. pH buffers for pH meters
  3. Thermometers for temperature calibration
  4. Multifunction calibrators for electronic instruments
  5. Pressure gauges for pressure calibration
  6. Tachometers for speed calibration

It’s important to establish regular calibration schedules for your laboratory equipment’s accuracy. This helps to maintain the reliability and precision of scientific instruments. By performing regular calibration you can be certain that the measurements you take are consistently accurate, and you can have confidence in the data your equipment gives you.

Invest in Discovery

You need to have the right laboratory equipment for scientific progress. Whether it’s basic tools like microscopes and centrifuges or more advanced gear like spectrophotometers and Polymerase Chain Reaction (PCR) machines, each piece is important for learning more and making advanced scientific discoveries. So, be sure you invest in updated equipment, prioritize safety, and welcome scientific innovation. When you work with BaneBio you’ll have the equipment and materials you need for experiments and scientific discoveries. Reach out to us for all of your laboratory needs.

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I-270 Innovation Labs: Partner for Life Science & Tech Companies

female scientist in life sciences who works with I-270 Innovation Labs working with microscope

Did you know there is a one-of-a-kind facility located in Frederick, MD which caters to life science and tech companies?  The I-270 Innovation Labs provides a niche lab space offering to launching start-ups, small and medium size companies as well as any company looking to establish a regional satellite location in the BioHealth Capital Region.  

With leases as short as 6 months and up to as long as needed, I-270 Innovation Labs offers flexibility to organizations who have short to medium term needs, or a need for high quality lab space to bridge organizational needs while a long-term space is being planned and constructed.  

As a member of the I-270 Innovation Labs, the monthly rent is inclusive of WiFi, Utilities, access to on demand lab equipment, conference & collaboration rooms, DI water, co-working infrastructure, biohazard waste disposal, autoclave and glass wash services, and so much more which makes I-270 Innovation Labs a great partner for all types of life science and tech companies!

Equipment and Supplies 

At the I-270 Innovation Labs, one of the featured amenities for their members is access to quality on demand lab equipment.  Through a strategic partnership with BaneBio, members can utilize on demand lab equipment that has been curated by the members of the I-270 Innovation Labs and supplied by BaneBio.  

All the equipment at I-270 Innovation Labs is maintained by BaneBio’s expert service team, which helps to minimize costly member equipment budgets and service calls.  I-270 Innovation Labs members also receive discounts through the partnership with BaneBio when either renting equipment as a part of a member sublease or an outright purchase of the equipment from BaneBio.  

Either way, I-270 Innovation Labs members can continue their scientific or tech work with confidence knowing BaneBio is available for equipment service and support.  

Logistics Services 

At the I-270 Innovation Labs, the strategic partnership with BaneBio assists their members by providing Lab Logistics Services.  BaneBio takes care of all the internal movements of equipment within the I-270 Innovation Labs.  

In addition, BaneBio offers Lab Logistics service to many companies in the BioHealth Capital Region.  Whether moving a single piece of equipment or a whole lab, contact the Lab Logistics experts at BaneBio for a quote.  I-270 Innovation Labs members can take advantage of this valuable service and receive discounts based on their membership.    

Room to Grow

At I-270 Innovation Labs, the heavy lifting of designing and building a great flexible lab space has already been done.  Every lab at the I-270 Innovation Labs includes dedicated outlets for various power requirements, ethernet ports for a more connected lab, HVAC to minimize possible cross contamination, wet lab ready plumbing, lab sink, lab benches, extra wide doors for large equipment, various size labs, anti-microbial epoxy flooring, and co-working infrastructure to minimize ‘office space’ within the lab and to provide more room for important lab work.  

The I-270 Innovation Labs is the right place to grow. There’s no need to start from scratch, commit to a fixed location or floor plan, or spread yourself too thin. Focus your resources on discovery and development. Invest more in talent and science, and less in space and equipment.

Flexibility

I-270 Innovation Labs was built with flexibility in mind.  From the design aspects of every lab to the amount of space needed and minimal lease terms, all types of organizations can find a home at I-270 Innovation Labs.  

Many similar facilities in the BioHealth Capital Region, which are run by local or state governments, can be more restrictive in leasing terms and will take equity from companies if they choose to move outside of the jurisdiction.  There is no equity assignment demanded from members of I-270 Innovation Labs, so that members can focus on making their business great and retain independence on where they move to next.  

Members of the I-270 Innovation Labs can access high-quality, purpose-built, Flex Wet Labs and Dry Labs, multimodal working spaces, and right-sized, key resources. If you need even greater flexibility, start out with an Individual Flex Bench, and get to innovate alongside Members at a similar growth stage and beyond, including established Enterprises.

The I-270 Innovation Labs is a unique offering for companies needing flexible lab space.  When compared to identifying a location, negotiating a lease, project management for buildout, and providing a personal or business guarantee for the duration of the lease, I-270 Innovation Labs is a No-Brainer for your next location.  

In case you need further incentive, to become a member at the I-270 Innovation Labs there is:

  • No Equity Surrender
  • No Personal Guaranty
  • No Financials/Projections
  • No Long-Term Commitment
  • No NNN/CAM
  • No Government Affiliation
  • No Fluff!

Whether you are getting ready to establish a regional satellite location, or expand into the BioHealth Capital Region, the I-270 Innovation Labs is the leading choice of tech and biotech enterprises that:

  • Have short- or medium-term needs for additional, highquality lab space or are unsure about their medium to long term requirements.
  • Do not currently have the bandwidth or financial resources to commission and manage the additional specialized infrastructure their operations demand.
  • Need or will need to quickly, and cost-effectively ramp up/down their operations.
  • Require on-demand access to reliable lab equipment and instrumentation, and/or cold and ULT storage with power backup options.
  • Want to provide teams or individuals with flexible, remote workplaces, and/or training location alternatives that include access to lab infrastructure and services.

Check out I-270 Innovation Labs and schedule a tour.

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10 Most Important Pieces of Lab Safety Equipment

lab station with lab safety equipment such as goggles and gloves

Safety is paramount in any laboratory setting, and understanding the potential risks involved is crucial. In this blog, we’ll highlight the ten essential pieces of equipment you should always have.

Lab Coats

These shield you from chemical spills and splashes, protecting your clothing and skin. Donning a lab coat reduces the risk of contamination and personal injury.

Safety Goggles

The importance of safeguarding your vision can’t be overstated. These goggles protect your eyes from potential injuries during experiments involving chemicals or other hazards.

Gloves

These prevent your hands from coming into contact with harmful substances. Wearing the right type of gloves for your specific laboratory tasks protects your skin. This is essential for your personal safety and contamination control.

Emergency Shower and Eyewash Station

In the event of a chemical spill or an eye exposure incident, it’s vital to have quick access to emergency showers and eyewash stations. Your skin and eyes are delicate, and even a few seconds of delay can result in a serious injury. Emergency showers and eyewash stations allow users to wash away hazardous materials, providing immediate decontamination.

Fire Extinguisher

A suitable fire extinguisher is a must-have in any lab to address potential fire hazards. First, It’s important to understand that not all fire extinguishers work the same way on all flames. Next, be sure you know how to use it effectively. Remember the acronym PASS which stands for:

  • Pull the pin
  • Aim
  • Squeeze
  • Sweep

Watch this video to see how to select and properly use the correct fire extinguisher.

Fume Hood

A fume hood is a ventilated enclosure designed to safely handle and contain potentially hazardous fumes, chemicals, or particulates. It’s equipped with an exhaust system that vents air away from the lab’s work areas. This protects users and the surrounding environment from exposure to harmful substances.

First Aid Kit

Every lab needs a fully-stocked first aid kit to care for minor injuries promptly. Make sure it has:

  • Medical gloves
  • Bandages, sterile pads, and adhesive tape
  • Scissors
  • Antiseptic cream
  • Breathing barrier
  • Burn dressings
  • Instant ice pack
  • Eye patch
  • Hand sanitizer

Be sure to regularly check and replenish the kit’s contents so it’s fully stocked and ready when needed.

Spill Kits

Accidents happen, and chemical spills can occur. Having spill kits on hand makes it possible to quickly clean up after such incidents, minimizing risks and overall environmental impact. Designed to soak up liquids, according to Iowa State University, these kits should contain:

  • A copy of the Spill Cleanup Protocol
  • Nitrile disposable gloves (8 mil)
  • Lab coat(s)
  • Safety goggles
  • N95 dust mask respirator(s)
  • Disposable shoe covers (booties)
  • Absorbent material, such as absorbent paper towels, granular absorbent material, etc. 
  • All-purpose disinfectants, such as normal household bleach (diluted 1:10) or an iodophor
  • Bucket for diluting disinfectant (this can be used to store the kit contents when not in use)
  • Tongs and/or forceps, and/ or dustpan and hand broom or squeegee, etc. (for picking up broken glass or other contaminated sharps)
  • Sharps waste container(s) 
  • Autoclavable biohazard waste bags
  • Biohazardous spill warning signs (“Biohazard Spill Kit”).

Ventilation System

Your lab needs to have an effective ventilation system. This maintains air quality and reduces exposure to harmful substances. It plays a key role in removing fumes and providing a safe breathing environment.

Safety Signs

Posting clear safety signs communicates potential hazards and guidelines effectively. They promote awareness and adherence to safety protocols, helping everyone work more safely.

Staying Safe

Prioritizing safety in your laboratory is non-negotiable. With these ten essential pieces of lab safety equipment, you can create a secure environment for yourself and your colleagues. Remember, safety should always come first in the lab. For more information, reach out to BaneBio today. 

Works Cited

Biohazard Spill Kit. Iowas State University Environmental Health and Safety. Retrieved November 10, 2023, from https://www.ehs.iastate.edu/research/biological/microbial/spill-cleanup/biohazard-spill-kit

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A Brief History of Centrifuges

scientist preparing to use centrifuge for experiment

Centrifuges are devices that can spin objects at high speeds in order to separate their components. This incredible tool has played an important role in various fields for many years. Let’s travel back through time and explore their fascinating history. 

Early Beginnings

In 1864, Antonin Prandtl invented a type of centrifuge machine to separate cream from milk in a dairy. In 1869, Swiss biologist and physician Friedrich Miescher built upon Prandtl’s invention. He became the first person to apply the principle of centrifugation in the lab.

However, the first truly continuous separating centrifugation product was developed by Gustaf de Laval. He took Prandt’s design and added turbines to it. In 1878 he and Oskar Lamm used that technology to patent a milk separator with one pipe for cream and another for milk. The principles of continuous centrifugation are still used today.

World War II

During World War II, centrifuges took on a new, darker role. They became invaluable tools in wartime research, specifically the Manhattan Project. They were used to separate isotopes, a crucial step in the creation of the atomic bomb. 

Medical and Scientific Advancements

As time went on, centrifuges made their way into the world of healthcare and scientific research. Centrifugation became crucial for tasks like blood separation, which is essential in diagnostics and treatment. In many laboratories, this tool still plays an important role in separating and analyzing substances, driving revolutionary scientific discoveries.

Modern Applications

Today, centrifuges have made their way into the fields of biology and food production. According to Science Direct, they are “One of the most useful and frequently employed techniques in the molecular biology laboratory” (Stephenson). In biology, they’re used to separate DNA, proteins, and cells, creating advancements in genetic research and disease diagnostics. In the food industry, they continue to be used to separate solid from liquid components, making processes like olive oil extraction and beer brewing more efficient. As technology has advanced, they have become faster, safer, and more accurate.

Conclusion

Centrifuges have come a long way from their early beginnings as mere spinning devices. They have left a lasting impact on various fields, from the arms races of World War II to today’s cutting-edge laboratories. Their relevance and importance remain strong and continue to grow, making them an indispensable tool in the modern world. For more information on how they can be best utilized in your lab, reach out to BaneBio!

Works Cited

Stephenson, Frank H. “Calculations for Molecular Biology and Biotechnology (Third Edition).” 2016, ScienceDirect, https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/centrifugation#:~:text=molecular%20biology%20laboratory.-,Centrifugation%20is%20used%20to%20collect%20cells%2C%20to%20precipitate%20DNA%2C%20to,using%20a%20variety%20of%20rotors

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Five Things to Consider When Buying Lab Equipment

lab worker using microscope

Whether you’re outfitting a brand-new laboratory or simply in the market to make some much-needed equipment purchases for your lab, there are many different factors to consider when buying lab equipment. Before you pull out your wallet or charge that microscope to your credit card, you might want to consider a few key details before purchasing lab equipment.

Budget

First, you’ll need to know how much you can afford to spend on equipment for your lab. It might not matter how badly you need something. Too pricey is too pricey. Luckily, it may be possible to apply for grants or other sources of funding so that you’ll be able to make those most needed and potentially life-saving purchases for your lab.

Brand/Quality

Naturally, you’ll want to do some research to ensure that any equipment you decide to buy is of the finest quality and includes the latest technology. You wouldn’t want to purchase something that’s already outdated or on the verge of being obsolete. That would just mean you’d have to replace it again in the not-too-distant future.

Doing a bit of research early on in your buying experience will save you time and money in the long run. You can always ask friends or colleagues for their opinion on equipment brands, as well as check out product reviews online. 

Features

In order to make certain that your laboratory’s equipment has the ultimate level of functionality, you’ll want to pay attention to the equipment’s features. Be sure to scrutinize specs, benefits, and uses.

In the end, you want to make sure that you’re buying high-quality equipment that will be long-lasting and capable of performing the tasks you need to have done. A piece of equipment can’t help you very much if it isn’t able to do the job, you’re purchasing it to do.

Warranty

No matter what type of lab equipment you decide to buy, get the warranty! If it’s not clear whether one is available, check with either your equipment’s seller or manufacturer to confirm it’s covered by a warranty. If on the off chance your new lab equipment malfunctions or fails to operate at its best capacity, having the warranty will save you a lot of hassle in either getting a replacement or a refund. 

New or Pre-Owned Equipment

Do you want to buy new or pre-owned lab equipment? Both of these choices will offer their own pros and cons. Buying new is always exciting, as it’s shiny, clean, and has never known wear and tear. It’s important in some cases, but don’t underestimate the durability and reliability of pre-owned equipment. If it’s been inspected, quality tested, and backed by warranty, you can rest assured it works as intended. Pre-owned products are always much lower in price than new ones, so your wallet will thank you!

Lab equipment is a big investment, and taking some time to research and weigh your options is an important step in the buying process. BaneBio is always ready to help you make the choice that’s best for your lab. Get in touch, so you can get to work!

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Manual-Fill vs. Automatic-Fill Dewars: What’s the Difference, and Why It Matters

scientist using cryogenic container

Cryogenic-storage options: decisions, decisions…

Labs make critical and calculated decisions daily, yet when it comes to choosing between a manual or automatic dewar system, investing depends on which type best suits your lab’s needs. 

What are liquid nitrogen dewars?

Liquid nitrogen dewars, invented by Sir. James Dewar of London in 1892, allows fluids to be maintained at low temperatures for a certain amount of time. Over the years, the dewar system has seen several iterations, innovations, and is simple in construction and design. The non-pressurized, air-jacketed structure includes two or more layers that are vacuum-sealed to prevent leaks, providing safety and thermal retention insulation. These freezers store tissues, cells, or other samples at temperatures reaching a frosty -196℃. The dewar has a loose-fitting plug or cap that is movable, preventing moisture and air from entering the chamber yet allowing liquid nitrogen evaporation. 

Manual-fill pros and cons

For the basic manual-fill dewar, the biggest win is its cost-effectiveness. The simple design means fewer problems with the freezer’s function. Once the tank is manually filled to the desired level, checking for evaporation rates, signs of frost on the outside of the tank, and monitoring for leaks is all it takes to keep it running in top form. Space within a lab is a precious commodity. These systems typically take up less real estate than their autofill counterpart by not requiring LN2 storage directly next to the freezer. 

One of the downsides of manual-fill systems includes checking liquid nitrogen numbers daily. The liquid nitrogen is generally topped off every two weeks, depending on how the freezer is accessed to retrieve items inside. Levels must be constantly watched, meaning there’s more room for error, which can affect samples. While investing in a monitoring system can help you keep an eye on LN2 tank levels, temperatures still must be monitored. That additional process equals time and energy that could be spent focused on other lab tasks. 

Autofill pros and cons

The name says it all: autofill systems do the heavy lifting for you. A liquid nitrogen source is connected to the tank and maintains LN2 levels automatically. Visual and audible alarms will alert if there is a system malfunction. Autofill also provides greater capacity to store LN2, alleviating the constant fear of running low. 

Here’s where autofill systems become tricky: there must always be an LN2 source stocked and functioning. Without it, the temperature could be compromised, leaving stored samples in a precarious situation. Autofill systems are pricier and they require more work to install and get running. Configuring the condensation collection system for moisture that pools on the transfer hose and installing the pressure regulator requires precision and accuracy for the system to work correctly. The investment in an autofill system can be hefty as can the uptick in electricity usage—huge considerations when considering budgets and the bottom line. 

Which is the system for you?

When you’re unsure which cryogenic system works best for your space, or an upgrade is in your future, let BaneBio help you sort through the details and secure the right storage for your lab’s needs!