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How COVID-19 Is Impacting Lab Operations

scientists talking at a laboratory table
The unemployment rate in the United States is currently hovering around 15%, the worst since the Great Depression. Women, Hispanics, and African Americans have been especially hard-hit and employment in the hospitality and retail sectors has also seen a sharp decline. According to a study conducted in April by market research firm BioInformatics, a partner of The Science Advisory Board, scientists and researchers are also concerned about what the immediate future holds for their employment outlook.

Of the 1,178 participants in the BioInformatics study, 74% were academic researchers and 26% were pharmaceutical or biotech scientists. On a regional basis, 33% of participants were based in North America, 31% in Europe, 24% in Asia, and the remaining 12% were from various other locations around the world.

Although many scientists are classified as essential employees, there are many who are not— and whose livelihoods have been adversely affected during the last 2–3 months by state and local stay-at-home orders. Following the trend set by the U.S. National Institutes of Health, many programs classified as non-essential have been temporarily shut down. In addition, many scientific researchers rely on grants to conduct their research— a funding source that has been all but curtailed during the quarantine. Many researchers have indicated that funds previously used to fund their ongoing studies have been diverted to maintain current animal studies and to pay core staff.

Today, approximately three months from the initial stay-at-home orders, many labs remain closed. The situation has especially dire implications for academic scientists, only 10% of whom responded that their labs were fully operational. More than 56% of academic laboratories remain affected— many more than pharmaceutical or industry laboratories, 27% of which are still closed. Of the remaining 612 labs that are partially or fully operational, 32% conduct research related to infectious diseases, compared with 68% that are not involved in infectious disease research. Surprisingly, a full 71% of research labs dedicated to infectious disease research report running at reduced capacity.

The productivity of those labs who have remained open has been adversely affected by physical distancing and other public health measures put in place to slow or minimize the spread of the highly contagious coronavirus. Unlike many industries who have been able to stay connected through video conferencing platforms like Zoom and GoToMeeting, this alternative has been far less effective in sustaining the collaborative efforts of scientists and researchers engaged in multidisciplinary projects

In April, according to the rating scale on the initial survey, scientists indicated that their work had been severely affected by the COVID-19 pandemic. A significant number of survey participants indicated that a severe economic downturn directly resulting from the outbreak would limit their ability to work. When broken down by research focus, infectious disease researchers working at operational labs reported slightly less concern over their ability to work than did their colleagues at academic labs or those involved in other types of research.

Very few areas of modern life have remained untouched by the pandemic, and the livelihoods of scientists and researchers are no exception. However, despite their current concern about how the pandemic and related economic crisis will affect their employment in the short-term, most expect to get back to conducting their research after the crisis passes. According to the recently updated U.S. Bureau of Labor Statistics’ Occupational Outlook Handbook, updated last September, epidemiologists, medical, biological, and clinical laboratory technologists and technicians, biochemists and biophysicists, microbiologists, and medical and research scientists are and will continue to be among the fastest-growing jobs between now and 2028.

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Starting a Lab: Begin with the End in Mind

medical research lab

When starting a new lab, it’s wise to take a page out of Steven Covey’s landmark book from 1989, The 7 Habits of Highly Effective People and “begin with the end in mind.”
What Covey means here is this: before you start your project— in this case building or designing a new laboratory— think about what its function and purpose are going to be when you’re finished. Answering those questions will give you a roadmap for everything else.

For example, is this a research lab? A cell culture lab may need sanitized areas, autoclaves, freezers, and incubators. Analytical labs require efficient air-conditioning and controllable humidity. If used for teaching purposes, include a whiteboard, a projector, storage space for backpacks and supplies, and writing surfaces/desks.

Laboratory Equipment

This will likely be your biggest expense, so don’t take it lightly. Start with a detailed list of what you are going to fulfill the purpose of your new lab. Next, inventory what might already be available to you somewhere else in your current facilities. Decide if it makes sense for you to buy, rent, or lease. If you decide to buy, you can sometimes find discounts available only to new, start-up labs. Used lab equipment from a reputable dealer is also a great way to save money.

Layout

Once you have your vision and obtained the equipment needed to bring it to fruition, it’s time to lay out the physical plant. Start by laying out your lab into different “zones”, each with varying degrees and types of hazards. Allocate various functions into the different zones so that the equipment in each is easily accessible but does not impede the flow of traffic. Speaking of access, be sure that lab entry is restricted to only authorized personnel. And finally, be sure there are multiple exits to be sure everyone is as safe as possible in the event of an emergency such as fire or building evacuation.

Safety

In addition to basics like fire extinguishers, make sure you have fire blankets, emergency showers (with easy-reach handles), eye-wash stations, gloves, masks, and any other task-specific safety equipment that might be needed. Require all staff to complete a compulsory safety training program that identifies potential hazards and appropriate procedures to address them.

Paperwork

There’s a lot of DIY involved in setting up a new lab, but there will also be some steps for which you’d be better served to consult a senior PI or mentor to make sure your start-up is in compliance. At the top of the list will likely be a HIRA (Hazard Identification and Risk Assessment). If your lab will be conducting tests on animals, you will need to obtain a license for animal testing and submit a research proposal to the applicable, regional regulatory bodies for approval. Depending on the type of reagents you use, you will also need to file forms with various regulatory agencies, especially if you use infectious agents or biological toxins.

Biosafety

Biosafety involves the measures taken when handling biological organisms/materials that are known to pose a threat to human health. Containment of the potentially hazardous organism or material in an emergency to reduce the number of exposures is critical. Your lab will need to demonstrate the availability and efficient implementation of both primary and secondary barriers.

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Lab Logistics: Steps to Take to Relocate Your Laboratory

packing up a science lab

At first, the thought of relocating your whole lab can be rather overwhelming. You may have been working in the same space for a number of years, and you know exactly where everything is right off the top of your head. With that said, laboratory relocation is a common experience, as change is inevitable in just about every industry. If you are facing an upcoming move and don’t know how to get started, we hope the tips below will help.

Start with Inventory

This should be the first step you take, and you should get going as soon as you know that the move is going to occur. By definition, a lab is going to have a lot of things that need to be inventoried, so this is quite possibly going to take a lot of time and effort. First, you’ll have the physical equipment that you use for your experiments – some of which is sure to be quite expensive. You may already have some form of inventory in place for all of your gear, but make sure it is up to date and accurate.

Also, there are the materials you use in the lab that will need to be counted and tracked. Depending on the focus of your work, it may be that some of these materials are hazardous, so keep that in mind and be working on a plan to safely and legally transport them to your next location.

Reduce the Size of the Move

One of the nice things about a relocation is that it can serve as an opportunity to pare down the size of your inventory and get rid of a few things that you no longer need. Maybe there are some materials which are used up and simply need to be disposed of in a responsible manner. Or, there might be a few pieces of equipment that are no longer required in your lab and can be sold on the used market. Reducing inventory will make the move easier and it will also help you to avoid cluttering up your new space unnecessarily.

Create a Comprehensive Plan

When you move from one home to the next in your personal life, you can afford to take a more casual approach, knowing that you’ll eventually find everything you need, like your toaster or blender. Such a relaxed approach is not appropriate for a lab move, however, as you need to get back up and running right away in your new location. With that in mind, create a detailed plan for how everything is going to be moved, when it will be moved, and who will do the moving. Including even the smallest details in your plan will help everyone stay on the same page from start to finish.

Be Flexible

Finally, remember that it’s nearly certain that something will go wrong along the way. Despite your careful planning efforts, something will go off-track – and that’s okay. Use your plan to get straightened out and be patient while working toward a successful conclusion.

As an expert laboratory logistics service provider, BaneBio offers multiple services to help simplify your laboratory relocation needs. Contact us today to learn more about packing, delivery, installation and much, much more!

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How to Quickly & Safely Prepare Samples

scientists with lab equipment

It’s hard to keep up with the flow of work in a busy lab, as some tasks simply take a long time to complete. The preparation of samples is one of those tasks in many cases. Depending on the type of sample being prepared, it might be hard to get the job done in time to keep up with everything else that needs to be done. Fortunately, there are methods available that can help to quickly and safely prepare samples. One such technique – the use of ultrasonic energy – is a popular option. Using the ultrasonic process can help with a variety of tasks, such as dispersing, emulsifying, mixing, dissolving, and more.

Following the Steps

As with everything that takes place in a lab, there are specific steps which should be followed when trying to prepare a sample quickly and properly. Once the samples are placed in an appropriate container, along with the right solvent, the ultrasonic process can begin. It is important, of course, to completely understand how to use the equipment involved in this process, as the results will only be accurate when the ultrasonic bath is employed in the correct manner.

One key point to consider when using ultrasonic energy is the matter of heat. Should your samples be heat sensitive, it will be necessary to use lab equipment which is capable of keeping the samples at an acceptable temperature during the process. For instance, some ultrasonic cleaners can use cooling coils to avoid the rising temperatures that would normally come with the use of ultrasonic energy.

Finding the Right Equipment

Purchasing new or used equipment for a laboratory is always a tricky job, and that is certainly the case when looking for gear that will permit you to prepare samples quickly and safely. For starters, you need to be able to find the right equipment for the specific jobs you need to complete, as your needs may vary even from similar labs. Also, you are going to have to remain within your budget, of course, as all purchases are subject to budgetary limitations of some kind. Only when you find equipment that both serves your needs and fits in your budget will you be able to move forward.

Once said equipment is purchased and put into action, regular cleaning and maintenance is necessary to get the most out of the investment. Machines which are capable of helping lab technicians quickly prepare samples are highly technical in nature and must be cared for properly. The key here is to pay close attention to the manufacturer’s instructions on cleaning and care. Each piece of equipment is unique, so it would be a mistake to assume that the care provided to one unit is going to be right for the others in the lab.

In a perfect world, you would have all the time you needed to prepare a sample without any sense of urgency. That is usually not the case, however, so using technologies which permit the rapid and safe preparation of samples is reality for many labs.

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Christmas In The Lab – Do’s and Don’ts

christmas-lab

It’s that time of year here in Maryland. The last of the yellow leaves have fallen, the air is frosty and the party season is in full swing. Evening rush hour starts a few hours earlier than normal, the malls are packed like sardines in a can, and the Metro is full of drunken people in Santa suits shouting at each other and snapping selfies.

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